Interactor 1: SIGIR (Q6IA17)
Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8)
Gene: SIGIRR

Interactor 2: SIGIR (Q6IA17)
Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8)
Gene: SIGIRR

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 12925853
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TIR~TIR
Common GO terms GO:0001960 - negative regulation of cytokine-mediated signaling pathway
GO:0005886 - plasma membrane
GO:0006953 - acute-phase response
GO:0007165 - signal transduction
GO:0016020 - membrane
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 410
Hs

1 410
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024