HitPredict

Interactor 1: GRHL2 (Q6ISB3)
Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3)
Gene: GRHL2

Interactor 2: GRHL1 (Q9NZI5)
Grainyhead-like protein 1 homolog (Mammalian grainyhead) (NH32) (Transcription factor CP2-like 2) (Transcription factor LBP-32)
Gene: GRHL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.884

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35013237, 12175488
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CP2~CP2
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus
and 6 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 625
Hs

1 618
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024