HitPredict

Interactor 1: M9PFK2 (M9PFK2)
HECT-type E3 ubiquitin transferase (EC 2.3.2.26)
Gene: Nedd4

Interactor 2: Q9VI00 (Q9VI00)
FI24305p1
Gene: DmelCG2641

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	38270169
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1005 Dm			1 429
+	Dm
		1367624 NEDD4_DROME (1-1005): 0: 950: 99.41		Q9VI00_DROME (1-429): 2.75e-158: 455: 100.00
+	Dm
		115611 M9PFK2_DROME (1-1005): 0: 960: 100.00		Q8SYU5_DROME (1-422): 8.94e-108: 327: 23.43
+	Dm
		1249345 NEDD4_DROME (1-1005): 0: 950: 99.41		Q8SYU5_DROME (1-422): 8.94e-108: 327: 23.43
+	Dm
		115613 M9PFK2_DROME (1-1005): 0: 960: 100.00		Q9VHZ7_DROME (1-315): 4.2e-88: 278: 32.51
+	Dm
		1367606 NEDD4_DROME (1-1005): 0: 950: 99.41		Q9VHZ7_DROME (1-315): 4.2e-88: 278: 32.51
+	Hs
		1285052 NED4L_HUMAN (63-1005): 0: 898: 47.59		ARRD3_HUMAN (10-410): 2.19e-108: 327: 26.12
+	Hs
		1252808 NED4L_HUMAN (63-1005): 0: 898: 47.59		ARRD2_HUMAN (13-410): 9.19e-103: 312: 24.57
+	Dm
		115612 M9PFK2_DROME (1-1005): 0: 960: 100.00		Q9VGU4_DROME (2-404): 1.08e-76: 249: 15.62
+	Hs
		1241907 NED4L_HUMAN (63-1005): 0: 898: 47.59		ARRD4_HUMAN (10-406): 2.67e-98: 302: 24.16
+	Dm
		1366431 NEDD4_DROME (1-1005): 0: 950: 99.41		Q9VGU4_DROME (2-404): 1.08e-76: 249: 15.62
+	Hs
		1299631 NED4L_HUMAN (63-1005): 0: 898: 47.59		TXNIP_HUMAN (4-396): 1.31e-87: 273: 21.17
+	Hs
		1234602 NED4L_HUMAN (63-1005): 0: 898: 47.59		ARRD1_HUMAN (6-416): 2.37e-80: 256: 19.10
+	Hs
		1285047 ITCH_HUMAN (56-1002): 0: 778: 30.64		ARRD3_HUMAN (10-410): 2.19e-108: 327: 26.12
+	Hs
		1252807 ITCH_HUMAN (56-1002): 0: 778: 30.64		ARRD2_HUMAN (13-410): 9.19e-103: 312: 24.57
+	Hs
		1241904 ITCH_HUMAN (56-1002): 0: 778: 30.64		ARRD4_HUMAN (10-406): 2.67e-98: 302: 24.16
+	Hs
		1294858 ITCH_HUMAN (56-1002): 0: 778: 30.64		TXNIP_HUMAN (4-396): 1.31e-87: 273: 21.17
+	Hs
		827260 ITCH_HUMAN (56-1002): 0: 778: 30.64		ARRB1_HUMAN (20-370): 1.12e-81: 259: 13.00
+	Hs
		1234600 ITCH_HUMAN (56-1002): 0: 778: 30.64		ARRD1_HUMAN (6-416): 2.37e-80: 256: 19.10
+	Hs
		1234607 WWP1_HUMAN (60-1002): 0: 776: 30.38		ARRD1_HUMAN (6-416): 2.37e-80: 256: 19.10
+	Hs
		686035 ITCH_HUMAN (56-1002): 0: 778: 30.64		ARRB2_HUMAN (20-364): 3.62e-78: 249: 12.56