HitPredict

Interactor 1: M9PFV2 (M9PFV2)
Myosin phosphatase targeting subunit 75D, isoform B
Gene: MYPT-75D

Interactor 2: PP1B (P48462)
Serine/threonine-protein phosphatase beta isoform (EC 3.1.3.16) (Protein flap wing)
Gene: flw

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	15269282, 21447707, 17007873, 25294943
Identification Methods	affinity chromatography technology, enzymatic study, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007476 - imaginal disc-derived wing morphogenesis GO:0017018 - myosin phosphatase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 635 Dm			1 330
+	Dm
		115662 M9PFV2_DROME (1-635): 5.24e-126: 387: 100.00		PP12_DROME (1-303): 0: 548: 85.48
+	Dm
		819281 Q8SY34_DROME (1-555): 2.86e-105: 336: 100.00		PP1B_DROME (1-330): 0: 592: 100.00
+	Dm
		1249016 Q8SY34_DROME (1-555): 2.86e-105: 336: 100.00		Q8T0U6_DROME (18-330): 0: 579: 99.68
+	Dm
		819272 Q86R99_DROME (42-458): 5.19e-90: 297: 30.95		PP1B_DROME (1-330): 0: 592: 100.00
+	Ce
		953872 P90902_CAEEL (115-523): 1.95e-102: 321: 38.61		GLC7A_CAEEL (3-329): 0: 568: 85.63
+	Ce
		1099876 Q95ZS1_CAEEL (115-523): 2.51e-101: 318: 38.25		GLC7A_CAEEL (3-329): 0: 568: 85.63
+	Hs
		225133 MYPT2_HUMAN (40-518): 3.14e-88: 297: 27.54		PP1B_HUMAN (1-329): 0: 581: 88.75
+	Hs
		225129 MYPT2_HUMAN (40-518): 3.14e-88: 297: 27.54		PP1G_HUMAN (1-330): 0: 572: 82.48
+	Hs
		225132 MYPT2_HUMAN (40-518): 3.14e-88: 297: 27.54		PP1A_HUMAN (1-326): 0: 570: 82.73
+	Dm
		1249926 Q9VUX6_DROME (42-534): 2.47e-81: 275: 28.89		Q8T0U6_DROME (18-330): 0: 579: 99.68
+	Mm
		926555 MYPT1_MOUSE (110-601): 1.31e-82: 282: 27.35		PP1G_MOUSE (1-330): 0: 572: 82.48
+	Mm
		906366 MYPT1_MOUSE (110-601): 1.31e-82: 282: 27.35		PP1A_MOUSE (1-326): 0: 570: 82.42
+	Mm
		906293 MYPT2_MOUSE (108-518): 8.3e-82: 279: 28.26		PP1A_MOUSE (1-326): 0: 570: 82.42
+	Hs
		906561 PP16A_HUMAN (23-539): 4.21e-81: 267: 38.43		PP1B_HUMAN (1-329): 0: 581: 88.75
+	Hs
		737978 PP16A_HUMAN (23-539): 4.21e-81: 267: 38.43		PP1G_HUMAN (1-330): 0: 572: 82.48
+	Hs
		906079 PP16A_HUMAN (23-539): 4.21e-81: 267: 38.43		PP1A_HUMAN (1-326): 0: 570: 82.73
+	Hs
		905838 ANK2_HUMAN (2-268): 2.34e-51: 194: 18.86		PP1A_HUMAN (1-326): 0: 570: 82.73
+	Hs
		906572 PP16B_HUMAN (19-211): 1.1e-22: 104: 12.50		PP1B_HUMAN (1-329): 0: 581: 88.75
+	Hs
		737999 PP16B_HUMAN (19-211): 1.1e-22: 104: 12.50		PP1G_HUMAN (1-330): 0: 572: 82.48
+	Hs
		906099 PP16B_HUMAN (19-211): 1.1e-22: 104: 12.50		PP1A_HUMAN (1-326): 0: 570: 82.73