Interactor 1: EXT1 (Q16394)
Exostosin-1 (EC 2.4.1.225) (Exostosin glycosyltransferase 1) (Heparan sulfate co-polymerase subunit EXT1) (Multiple exostoses protein 1) (N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase)
Gene: EXT1
Interactor 2: EXT2 (Q93063)
Exostosin-2 (EC 2.4.1.224) (Exostosin glycosyltransferase 2) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Heparan sulfate co-polymerase subunit EXT1) (Multiple exostoses protein 2)
Gene: EXT2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.79 | 1.00 | 0.892 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10679296, 28514442, 33961781, unassigned3799 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Exostosin~Exostosin, Exostosin~Glyco_transf_64, Glyco_transf_64~Glyco_transf_64 |
| Common GO terms | GO:0000139 - Golgi membrane GO:0000271 - polysaccharide biosynthetic process GO:0001503 - ossification GO:0005783 - endoplasmic reticulum GO:0005794 - Golgi apparatus and 18 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
