HitPredict

Interactor 1: MZT2B (Q6NZ67)
Mitotic-spindle organizing protein 2B (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2B)
Gene: MZT2B

Interactor 2: GCP5 (Q96RT8)
Gamma-tubulin complex component 5 (GCP-5)
Gene: TUBGCP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	26186194, 28514442, 33961781, 26496610, 20360068
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000931 - gamma-tubulin ring complex GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 1024
+	Hs
		1159877 MZT2A_HUMAN (1-158): 4.36e-83: 243: 96.20		GCP5_HUMAN (1-1024): 0: 1138: 100.00
+	Hs
		1159887 MZT2A_HUMAN (1-158): 4.36e-83: 243: 96.20		GCP4_HUMAN (270-1017): 1.94e-154: 474: 14.64
+	Hs
		1157539 MZT2B_HUMAN (1-158): 3.38e-81: 238: 100.00		GCP4_HUMAN (270-1017): 1.94e-154: 474: 14.64
+	Hs
		70862 MZT2B_HUMAN (1-158): 3.38e-81: 238: 100.00		B2RWN4_HUMAN (578-1017): 4.77e-85: 304: 22.39
+	Hs
		1157523 MZT2B_HUMAN (1-158): 3.38e-81: 238: 100.00		GCP6_HUMAN (578-1017): 7.59e-85: 303: 22.39
+	Hs
		1159875 MZT2A_HUMAN (1-158): 4.36e-83: 243: 96.20		GCP3_HUMAN (216-692): 2.22e-60: 225: 11.25
+	Hs
		1159881 MZT2A_HUMAN (1-158): 4.36e-83: 243: 96.20		GCP2_HUMAN (250-623): 2.18e-59: 222: 13.37
+	Hs
		1157520 MZT2B_HUMAN (1-158): 3.38e-81: 238: 100.00		GCP3_HUMAN (216-692): 2.22e-60: 225: 11.25
+	Hs
		1157527 MZT2B_HUMAN (1-158): 3.38e-81: 238: 100.00		GCP2_HUMAN (250-623): 2.18e-59: 222: 13.37
+	Hs
		1157528 MZT2B_HUMAN (1-158): 3.38e-81: 238: 100.00		Q9BVR6_HUMAN (423-820): 3.02e-54: 194: 11.96