HitPredict

Interactor 1: M9PGE1 (M9PGE1)
Dpr-interacting protein alpha, isoform B
Gene: DIP-alpha

Interactor 2: X2J8X8 (X2J8X8)
Defective proboscis extension response 6, isoform F
Gene: dpr6

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.915

Property	Details
Experiments	23827685, 26687361, 30467080, 32358559
Identification Methods	affinity chromatography technology, pull down, x-ray crystallography
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Ig_3~I-set, I-set~V-set, Ig_3~Ig_3, Ig_3~V-set
Common GO terms	GO:0032589 - neuron projection membrane GO:0050808 - synapse organization
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 432 Dm			1 396
+	Dm
		115781 M9PGE1_DROME (1-423): 5.72e-87: 273: 100.00		Q9VT83_DROME (48-288): 6.78e-64: 211: 54.17
+	Dm
		1373879 Q9W4R3_DROME (22-364): 7.17e-46: 168: 17.98		Q9VT83_DROME (48-288): 6.78e-64: 211: 54.17
+	Dm
		1373877 Q9W4R3_DROME (22-364): 7.17e-46: 168: 17.98		Q9VT76_DROME (1-279): 2.71e-62: 203: 97.85
+	Dm
		51388 A8JNC7_DROME (22-346): 3.94e-41: 153: 15.85		A1Z6H9_DROME (71-271): 1.37e-62: 205: 44.98
+	Hs
		530171 NCAM1_HUMAN (23-424): 8.35e-62: 216: 11.82		OPCM_HUMAN (49-269): 9.1e-31: 122: 18.14
+	Dm
		1308435 Q9BN17_DROME (2-320): 1.02e-38: 151: 16.57		Q9VAR6_DROME (51-385): 3.71e-53: 183: 22.61
+	Mm
		1142035 MUSK_MOUSE (2-214): 1.28e-39: 153: 20.93		MUSK_MOUSE (69-388): 1.09e-48: 178: 17.18
+	Hs
		507819 NCAM1_HUMAN (23-424): 8.35e-62: 216: 11.82		FGFR1_HUMAN (2-176): 5.32e-23: 103: 14.05
+	Mm
		530206 NCAM1_MOUSE (23-424): 2.14e-59: 211: 11.82		CNTN2_MOUSE (68-396): 9.35e-22: 99.7: 14.92
+	Mm
		1149039 CNTN4_MOUSE (16-430): 1.55e-50: 185: 12.70		CNTN4_MOUSE (69-396): 3.37e-26: 113: 13.24
+	Ce
		103933 SAX3_CAEEL (121-424): 9.6e-39: 151: 14.79		SAX3_CAEEL (73-396): 5.31e-36: 142: 13.71
+	Mm
		530213 NCAM1_MOUSE (23-424): 2.14e-59: 211: 11.82		DSCAM_MOUSE (4-359): 1.6e-14: 77.7: 11.62
+	Hs
		1378225 ROBO1_HUMAN (109-428): 2.38e-45: 170: 10.74		ROBO1_HUMAN (172-396): 3.55e-19: 92: 13.44
+	Hs
		1336275 ROBO1_HUMAN (109-428): 2.38e-45: 170: 10.74		ROBO2_HUMAN (172-396): 1.65e-18: 90: 13.01
+	Hs
		1336269 ROBO2_HUMAN (113-428): 2.31e-42: 161: 12.42		ROBO2_HUMAN (172-396): 1.65e-18: 90: 13.01
+	Hs
		1061308 NTRI_HUMAN (32-313): 7.1e-33: 128: 15.52		OPCM_HUMAN (49-269): 9.1e-31: 122: 18.14
+	Hs
		234601 ROBO1_HUMAN (109-428): 2.38e-45: 170: 10.74		DSCAM_HUMAN (4-359): 8.23e-15: 78.5: 11.62
+	Rn
		222935 ROBO1_RAT (109-428): 8.75e-46: 171: 11.04		DCC_RAT (2-374): 5.67e-13: 72.7: 11.39
+	Dm
		65500 A8JNC7_DROME (22-346): 3.94e-41: 153: 15.85		Q9VFD9_DROME (57-195): 1.23e-09: 61.9: 19.01