HitPredict

Interactor 1: MED27 (Q6P2C8)
Mediator of RNA polymerase II transcription subunit 27 (Cofactor required for Sp1 transcriptional activation subunit 8) (CRSP complex subunit 8) (Mediator complex subunit 27) (P37 TRAP/SMCC/PC2 subunit) (Transcriptional coactivator CRSP34)
Gene: MED27

Interactor 2: H2AW (Q9P0M6)
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Gene: MACROH2A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 311 Hs			1 372
+	Hs
		260912 MED27_HUMAN (1-311): 0: 568: 100.00		H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31
+	Hs
		1158900 MED27_HUMAN (1-311): 0: 568: 100.00		H2A2B_HUMAN (1-123): 1.24e-64: 203: 63.49
+	Hs
		1158917 MED27_HUMAN (1-311): 0: 568: 100.00		H2A1J_HUMAN (1-125): 2.23e-64: 202: 60.94
+	Hs
		1158918 MED27_HUMAN (1-311): 0: 568: 100.00		H2AJ_HUMAN (1-126): 1.06e-63: 201: 60.47