Interactor 1: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Interactor 2: AAR2 (Q9Y312)
Protein AAR2 homolog (AAR2 splicing factor homolog)
Gene: AAR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.963

The method score is based on:

Property Details
Experiments 28515276, 34079125, 35271311, 26186194, 28514442, 28561026, 33961781
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAR2~PRP8_domainIV, AAR2~U5_2-snRNA_bdg, AAR2~U6-snRNA_bdg
Common GO terms GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0005682 - U5 snRNP
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 2335
Hs

1 384
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024