Protein: TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1 (Transcription-associated protein 1) (p400 kDa component of SAGA)

Gene: TRA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 134
UniProt ID: P38811

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0006351 - DNA-templated transcription
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

805222

EAF1
Chromatin modification-related protein EAF1

7

1

Small-scale

0.960

High

793915

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

4

13

High-throughput

0.895

High

805209

ADA2
SAGA complex subunit ADA2

17

7

Small-scale

0.764

High

805231

ESA1
Histone acetyltransferase ESA1

19

12

Small-scale

0.764

High

762954

SPT7
SAGA complex subunit SPT7

19

19

Small-scale

0.764

High

805190

EPL1
Enhancer of polycomb-like protein 1

14

3

Small-scale

0.760

High

805213

GCN5
Histone acetyltransferase GCN5

14

18

Small-scale

0.760

High

805234

HFI1
SAGA complex subunit HFI1

13

2

Small-scale

0.758

High

805244

SUS1
SAGA complex subunit SUS1

12

3

Small-scale

0.757

High

805214

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

12

4

Small-scale

0.756

High

805179

SPT8
SAGA complex subunit SPT8

8

1

Small-scale

0.750

High

805199

SGF73
SAGA complex subunit SGF73

8

6

Small-scale

0.747

High

805220

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

8

4

Small-scale

0.747

High

805196

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

8

9

Small-scale

0.747

High

805198

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

7

4

Small-scale

0.745

High

449456

SPT3
SAGA complex subunit SPT3

7

3

Small-scale

0.741

High

805202

AF9
Protein AF-9 homolog

6

6

Small-scale

0.733

High

738151

NGG1
SAGA complex subunit NGG1

6

3

Small-scale

0.729

High

805197

SPT20
SAGA complex subunit SPT20

11

0

Small-scale

0.725

High

805120

YNG2
Chromatin modification-related protein YNG2

5

12

Small-scale

0.721

High

805200

SWC4
SWR1-complex protein 4

4

4

Small-scale

0.699

High

805207

ARP4
Actin-related protein 4

4

6

Small-scale

0.697

High

676638

SGF29
SAGA complex subunit SGF29

4

5

Small-scale

0.694

High

805241

EAF3
Chromatin modification-related protein EAF3

4

3

Small-scale

0.691

High

805182

EAF5
Chromatin modification-related protein EAF5

5

0

Small-scale

0.686

High

805201

EAF7
Chromatin modification-related protein EAF7

5

0

Small-scale

0.684

High

805211

SGF11
SAGA complex subunit SGF11

5

0

Small-scale

0.684

High

805233

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

4

3

Small-scale

0.683

High

805195

EAF6
Chromatin modification-related protein EAF6

4

0

Small-scale

0.667

High

408411

GAL4
Regulatory protein GAL4

3

1

Small-scale

0.654

High

805218

LCD1
DNA damage checkpoint protein LCD1

1

1

Small-scale

0.647

High

805187

SA185
SIT4-associating protein SAP185

2

5

High-throughput

0.628

High

395241

GCN4
General control transcription factor GCN4

3

0

Small-scale

0.623

High

745727

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

8

High-throughput

0.618

High

419727

H2A2
Histone H2A.2

2

10

Small-scale

0.611

High

754208

MSN4
Zinc finger protein MSN4

2

3

High-throughput

0.601

High

805243

H2AZ
Histone H2A.Z

2

8

Small-scale

0.601

High

734422

BTAF1
TATA-binding protein-associated factor MOT1

2

11

Small-scale

0.584

High

805177

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

16

Small-scale

0.575

High

670683

SIS1
Protein SIS1

2

7

Small-scale

0.571

High

736644

ASF1
Histone chaperone ASF1

2

1

Small-scale

0.571

High

805205

ACT
Actin

2

1

Small-scale

0.571

High

805206

H3
Histone H3

2

10

High-throughput

0.571

High

805236

RIO1
Serine/threonine-protein kinase RIO1

2

4

High-throughput

0.571

High

792795

ANM1
Protein arginine N-methyltransferase 1

1

2

Small-scale

0.541

High

452735

ADR1
Regulatory protein ADR1

1

1

High-throughput

0.536

High

466789

SWI5
Transcriptional factor SWI5

1

4

High-throughput

0.536

High

534057

HSF
Heat shock transcription factor

1

2

High-throughput

0.536

High

794742

RTG3
Retrograde regulation protein 3

1

1

High-throughput

0.536

High

801821

KSP1
Serine/threonine-protein kinase KSP1

1

20

High-throughput

0.536

High

805210

IMA1
Importin subunit alpha

1

6

High-throughput

0.536

High

805232

CTI6
Histone deacetylase complex subunit CTI6

1

1

High-throughput

0.536

High

626503

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.513

High

805224

RSC3
Chromatin structure-remodeling complex protein RSC3

1

0

High-throughput

0.513

High

805239

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.513

High

805185

MSL1
U2 small nuclear ribonucleoprotein B''

1

5

High-throughput

0.508

High

751042

XRS2
DNA repair protein XRS2

1

1

Small-scale

0.501

High

548770

MCM1
Pheromone receptor transcription factor

1

1

Small-scale

0.481

High

602007

CBF1
Centromere-binding protein 1

1

3

Small-scale

0.481

High

805189

FKH2
Fork head protein homolog 2

1

5

Small-scale

0.481

High

805193

ZAP1
Zinc-responsive transcriptional regulator ZAP1

1

2

Small-scale

0.481

High

364516

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.479

High

419423

H2A1
Histone H2A.1

1

10

Small-scale

0.479

High

645405

XRN1
5'-3' exoribonuclease 1

1

2

High-throughput

0.479

High

647765

RFA1
Replication factor A protein 1

1

7

Small-scale

0.479

High

707034

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

712981

MCM2
DNA replication licensing factor MCM2

1

8

Small-scale

0.479

High

721370

MCM4
DNA replication licensing factor MCM4

1

9

Small-scale

0.479

High

736514

SFP1
Transcription factor SFP1

1

3

Small-scale

0.479

High

743023

SWI3
SWI/SNF complex subunit SWI3

1

7

High-throughput

0.479

High

744296

CHD1
Chromo domain-containing protein 1

1

8

Small-scale

0.479

High

781034

TTI1
TEL2-interacting protein 1

1

16

High-throughput

0.479

High

800699

RCK1
Serine/threonine-protein kinase RCK1

1

17

High-throughput

0.479

High

805184

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.479

High

805186

DSN1
Kinetochore-associated protein DSN1

1

3

High-throughput

0.479

High

805194

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.479

High

805203

APJ1
J domain-containing protein APJ1

1

8

High-throughput

0.479

High

805212

TOM1
E3 ubiquitin-protein ligase TOM1

1

7

High-throughput

0.479

High

805216

RUVB1
RuvB-like protein 1

1

19

High-throughput

0.479

High

805217

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

805235

SCC1
Sister chromatid cohesion protein 1

1

3

High-throughput

0.479

High

805238

SMT3
Ubiquitin-like protein SMT3

1

4

High-throughput

0.479

High

638799

REB1
DNA-binding protein REB1

1

0

Small-scale

0.460

High

561473

TBP
TATA-box-binding protein

1

0

High-throughput

0.458

High

569531

HAP4
Transcriptional activator HAP4

1

0

Small-scale

0.458

High

594357

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

624910

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

Small-scale

0.458

High

734968

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

747838

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

763882

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

764067

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

805178

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.458

High

805191

SAC3
Nuclear mRNA export protein SAC3

1

0

Small-scale

0.458

High

805215

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

805219

TAF7
Transcription initiation factor TFIID subunit 7

1

0

High-throughput

0.458

High

805221

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

805223

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

805230

SGO1
Shugoshin

1

0

High-throughput

0.458

High

381096

H2B1
Histone H2B.1

1

7

High-throughput

0.445

High

382087

H4
Histone H4

1

6

High-throughput

0.445

High

518014

SSBP1
Single-stranded nucleic acid-binding protein

1

2

High-throughput

0.445

High

523874

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

526637

HSP72
Heat shock protein SSA2

1

12

High-throughput

0.445

High

544796

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

547791

NHP6A
Non-histone chromosomal protein 6A

1

5

High-throughput

0.445

High

619427

MED14
Mediator of RNA polymerase II transcription subunit 14

1

1

High-throughput

0.445

High

671524

SWI4
Regulatory protein SWI4

1

4

High-throughput

0.445

High

675983

MAS5
Mitochondrial protein import protein MAS5

1

8

High-throughput

0.445

High

741534

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

752963

IXR1
Intrastrand cross-link recognition protein

1

4

High-throughput

0.445

High

754151

MSN2
Zinc finger protein MSN2

1

2

High-throughput

0.445

High

781739

SET3
SET domain-containing protein 3

1

5

High-throughput

0.445

High

805192

TRM61
tRNA

1

1

High-throughput

0.445

High

805204

CRZ1
Transcriptional regulator CRZ1

1

2

High-throughput

0.445

High

805229

THP1
Nuclear mRNA export protein THP1

1

1

Small-scale

0.445

High

805240

IES3
Ino eighty subunit 3

1

1

High-throughput

0.445

High

805242

CAF1A
Chromatin assembly factor 1 subunit A

1

2

High-throughput

0.445

High

561309

DPOLA
DNA polymerase alpha catalytic subunit A

1

2

Small-scale

0.437

High

794974

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

805226

VAM6
Vacuolar morphogenesis protein 6

1

4

High-throughput

0.437

High

448169

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

805228

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

704782

MSP1
Outer mitochondrial transmembrane helix translocase

1

5

High-throughput

0.407

High

805180

TCPB
T-complex protein 1 subunit beta

1

2

High-throughput

0.407

High

805208

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

16

High-throughput

0.407

High

805227

NOP6
Nucleolar protein 6

1

0

High-throughput

0.279

Low

805237

ATG34
Autophagy-related protein 34

1

0

High-throughput

0.279

Low

672799

ELO2
Fatty acid elongase 2

1

0

High-throughput

0.249

Low

797736

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

805181

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

805183

ICE2
Protein ICE2

1

0

High-throughput

0.232

Low

805188

SYS1
Protein SYS1

1

0

High-throughput

0.232

Low

805225

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025