HitPredict

Interactor 1: PKN3 (Q6P5Z2)
Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN-beta) (Protein-kinase C-related kinase 3)
Gene: PKN3

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 889 Hs			1 779
+	Hs
		1082035 PKN2_HUMAN (13-884): 0: 894: 49.26		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1081971 PKN1_HUMAN (27-883): 0: 888: 51.05		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1148919 PKN3_HUMAN (1-889): 0: 974: 100.00		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		566481 KPCA_HUMAN (379-889): 6.46e-167: 503: 33.65		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		408682 KPCB_HUMAN (401-887): 1.3e-164: 497: 34.14		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		682210 AKT2_HUMAN (431-883): 8.79e-159: 474: 35.15		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		682023 AKT1_HUMAN (431-883): 2.39e-158: 473: 34.72		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		623884 KPCL_HUMAN (521-886): 8.34e-152: 464: 41.85		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		981062 KPCT_HUMAN (502-884): 1.34e-148: 456: 40.63		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		270445 KS6A5_HUMAN (453-815): 3.64e-96: 321: 21.94		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		984534 KPCD_HUMAN (564-886): 1.29e-90: 303: 48.31		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		566377 KPCA_HUMAN (379-889): 6.46e-167: 503: 33.65		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		408612 KPCB_HUMAN (401-887): 1.3e-164: 497: 34.14		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		681831 AKT1_HUMAN (431-883): 2.39e-158: 473: 34.72		GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92
+	Mm
		930572 KPCG_MOUSE (401-889): 4.51e-156: 476: 33.33		CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40
+	Hs
		397159 KPCG_HUMAN (401-889): 1.25e-156: 477: 33.33		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Rn
		1144020 AKT3_RAT (431-883): 5.11e-155: 465: 35.08		CAPS1_RAT (11-428): 1.59e-46: 181: 10.23
+	Hs
		969077 KPCE_HUMAN (476-887): 1.37e-149: 460: 37.59		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		984488 KPCD_HUMAN (564-886): 1.29e-90: 303: 48.31		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		1071703 KS6A2_HUMAN (481-868): 5.85e-91: 305: 23.78		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61