Interactor 1: WDR59 (Q6PJI9)
GATOR2 complex protein WDR59 (WD repeat-containing protein 59)
Gene: WDR59

Interactor 2: SEH1 (Q96EE3)
Nucleoporin SEH1 (GATOR2 complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein)
Gene: SEH1L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 26496610, 28199306, 35831510
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains WD40~WD40
Common GO terms GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0031669 - cellular response to nutrient levels
GO:0032008 - positive regulation of TOR signaling
GO:0034198 - cellular response to amino acid starvation
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 974
Hs

1 360
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024