HitPredict

Interactor 1: Q6PK50 (Q6PK50)
Heat shock protein HSP 90-beta
Gene: HSP90AB1

Interactor 2: UN45B (Q8IWX7)
Protein unc-45 homolog B (Unc-45B) (SMUNC45)
Gene: UNC45B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 351 Hs			1 931
+	Hs
		438336 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		UN45B_HUMAN (1-931): 0: 998: 100.00
+	Hs
		111940 K9JA46_HUMAN (1-350): 1.31e-173: 501: 84.92		UN45B_HUMAN (1-931): 0: 998: 100.00
+	Hs
		438524 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		UN45A_HUMAN (6-929): 0: 924: 56.65
+	Hs
		438533 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		RPAP3_HUMAN (1-327): 6e-46: 178: 16.12
+	Hs
		1162526 Q6PK50_HUMAN (1-345): 2.04e-180: 505: 100.00		RPAP3_HUMAN (1-327): 6e-46: 178: 16.12
+	Hs
		297025 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		TOM70_HUMAN (2-387): 1.32e-40: 161: 15.82
+	Hs
		438590 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		Z3H7B_HUMAN (3-162): 2.21e-39: 160: 26.86
+	Mm
		513680 HS90B_MOUSE (1-345): 1.63e-176: 509: 99.71		PPP5_MOUSE (4-155): 1e-36: 147: 27.45
+	Hs
		438021 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		PPP5_HUMAN (2-155): 1.26e-36: 147: 28.39
+	Hs
		1162522 Q6PK50_HUMAN (1-345): 2.04e-180: 505: 100.00		Q9BPW0_HUMAN (2-155): 7.04e-37: 147: 28.39
+	Mm
		513709 HS90B_MOUSE (1-345): 1.63e-176: 509: 99.71		CHIP_MOUSE (6-146): 9.32e-37: 142: 27.66
+	Hs
		213454 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		SGTA_HUMAN (4-126): 6.85e-37: 143: 30.89
+	Hs
		111935 K9JA46_HUMAN (1-350): 1.31e-173: 501: 84.92		PPP5_HUMAN (2-155): 1.26e-36: 147: 28.39
+	Hs
		438621 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		CHIP_HUMAN (6-146): 9.82e-37: 142: 27.66
+	Hs
		174561 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		OGT1_HUMAN (6-407): 2.59e-28: 124: 12.90
+	Hs
		174556 HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92		OGT1_HUMAN (6-407): 2.59e-28: 124: 12.90
+	Hs
		437930 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		STIP1_HUMAN (4-427): 5.12e-27: 118: 12.82
+	Hs
		111934 K9JA46_HUMAN (1-350): 1.31e-173: 501: 84.92		STIP1_HUMAN (4-427): 5.12e-27: 118: 12.82
+	Hs
		438201 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		TOM34_HUMAN (7-131): 9.33e-25: 107: 26.92
+	Hs
		438106 HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00		PPID_HUMAN (9-142): 2.04e-09: 62.4: 28.38