Protein: CBR4
3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (3-ketoacyl-[acyl-carrier-protein] reductase beta subunit) (KAR beta subunit) (Carbonyl reductase family member 4) (CBR4) (Quinone reductase CBR4) (EC 1.6.5.10) (Short chain dehydrogenase/reductase family 45C member 1)

Gene: CBR4
Organism: Homo sapiens
Interactions: 39
UniProt ID: Q8N4T8

Gene Ontology (top 5):
GO:0003955 - NAD(P)H dehydrogenase (quinone) activity
GO:0004316 - 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006633 - fatty acid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1326813

DHB8
(3R)-3-hydroxyacyl-CoA dehydrogenase

4

17

High-throughput

0.895

High

1326821

SEPT3
Neuronal-specific septin-3

4

1

High-throughput

0.630

High

1179737

ZXDC
Zinc finger protein ZXDC

2

1

High-throughput

0.553

High

166683

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

2

High-throughput

0.536

High

177569

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

1

High-throughput

0.536

High

856311

IF2M
Translation initiation factor IF-2, mitochondrial

1

4

High-throughput

0.536

High

1061344

CP24A
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

1

1

High-throughput

0.536

High

1138858

SYLM
Leucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

1216264

NDUF5
Arginine-hydroxylase NDUFAF5, mitochondrial

1

1

High-throughput

0.536

High

1244559

SYDM
Aspartate--tRNA ligase, mitochondrial

1

4

High-throughput

0.536

High

1310226

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

1326814

SYNM
Asparaginyl-tRNA synthetase

1

4

High-throughput

0.536

High

1326815

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

2

High-throughput

0.536

High

1326816

SYTM
Threonine--tRNA ligase, mitochondrial

1

2

High-throughput

0.536

High

1326817

MTG2
Mitochondrial ribosome-associated GTPase 2

1

3

High-throughput

0.536

High

1326819

NPS3A
Protein NipSnap homolog 3A

1

1

High-throughput

0.536

High

296136

GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

1

0

High-throughput

0.513

High

846017

CACP
Carnitine O-acetyltransferase

1

0

High-throughput

0.513

High

869192

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

926100

DPOG1
DNA polymerase subunit gamma-1

1

0

High-throughput

0.513

High

1160416

TAZ
Tafazzin

1

0

High-throughput

0.513

High

1326818

RSAD1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial

1

0

High-throughput

0.513

High

564051

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.494

High

260911

RAMP3
Receptor activity-modifying protein 3

1

1

High-throughput

0.489

High

326737

DUS14
Dual specificity protein phosphatase 14

1

2

High-throughput

0.489

High

593437

PGFRA
Platelet-derived growth factor receptor alpha

1

3

High-throughput

0.489

High

822159

PSB10
Proteasome subunit beta type-10

1

3

High-throughput

0.489

High

1326812

LRC15
Leucine-rich repeat-containing protein 15

1

1

High-throughput

0.489

High

1162423

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

3

Small-scale

0.479

High

294011

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

767262

MERL
Merlin

1

1

High-throughput

0.437

High

1325495

FBXW8
F-box/WD repeat-containing protein 8

1

1

High-throughput

0.437

High

1326820

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.437

High

538784

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

5

High-throughput

0.407

High

1197828

S39AC
Zinc transporter ZIP12

1

1

High-throughput

0.407

High

749358

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

1307344

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

0

High-throughput

0.279

Low

1326811

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1326822

CLC4E
C-type lectin domain family 4 member E

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025