HitPredict

Interactor 1: CORO6 (Q6QEF8)
Coronin-6 (Coronin-like protein E) (Clipin-E)
Gene: CORO6

Interactor 2: COR1B (Q9BR76)
Coronin-1B (Coronin-2)
Gene: CORO1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DUF1899~WD40, DUF1899~WD40_4, WD40~WD40, WD40~WD40_4
Common GO terms	GO:0007015 - actin filament organization GO:0016477 - cell migration GO:0051015 - actin filament binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 472 Hs			1 489
+	Hs
		1163316 CORO6_HUMAN (1-472): 5.34e-133: 394: 100.00		COR1C_HUMAN (4-484): 1.14e-119: 360: 72.77
+	Hs
		678279 CORO6_HUMAN (1-472): 5.34e-133: 394: 100.00		COR1A_HUMAN (4-481): 3.61e-109: 333: 63.47
+	Hs
		1309913 COR1B_HUMAN (1-470): 2.03e-114: 347: 67.15		COR1C_HUMAN (4-484): 1.14e-119: 360: 72.77
+	Hs
		678320 COR1A_HUMAN (1-463): 1.82e-110: 336: 67.24		COR1C_HUMAN (4-484): 1.14e-119: 360: 72.77
+	Mm
		292621 COR1A_MOUSE (1-463): 8.64e-110: 334: 67.46		COR1C_MOUSE (4-484): 1.01e-119: 360: 73.39
+	Mm
		292620 COR1B_MOUSE (1-470): 7.9e-116: 350: 68.05		COR1A_MOUSE (4-481): 3.96e-108: 330: 63.05
+	Hs
		678302 COR1B_HUMAN (1-470): 2.03e-114: 347: 67.15		COR1A_HUMAN (4-481): 3.61e-109: 333: 63.47
+	Mm
		292586 COR1A_MOUSE (1-463): 8.64e-110: 334: 67.46		COR1A_MOUSE (4-481): 3.96e-108: 330: 63.05
+	Hs
		678297 COR1A_HUMAN (1-463): 1.82e-110: 336: 67.24		COR2A_HUMAN (1-487): 6.49e-96: 301: 44.13
+	Hs
		1271431 COR2A_HUMAN (1-472): 8.75e-94: 295: 43.75		COR2B_HUMAN (1-486): 2.65e-93: 293: 42.33
+	Hs
		678293 COR1A_HUMAN (1-463): 1.82e-110: 336: 67.24		POC1B_HUMAN (4-253): 3.75e-59: 204: 17.60
+	Hs
		1163297 CORO6_HUMAN (1-472): 5.34e-133: 394: 100.00		POC1A_HUMAN (256-436): 2.61e-19: 91.9: 9.24
+	Hs
		678289 COR1A_HUMAN (1-463): 1.82e-110: 336: 67.24		POC1A_HUMAN (256-436): 2.61e-19: 91.9: 9.24
+	Sc
		987352 CORO_YEAST (1-449): 1.48e-96: 306: 37.58		CORO_YEAST (1-166): 8.49e-13: 72.7: 12.00
+	Hs
		792949 WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55		LIS1_HUMAN (257-482): 1.43e-18: 89.6: 9.69