Protein: H2B1A
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)

Gene: H2B1A, H2BC1
Organism: Homo sapiens
Interactions: 185
UniProt ID: Q96A08

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0000786 - nucleosome
GO:0001674 - female germ cell nucleus
GO:0003677 - DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

888237

MCM2
DNA replication licensing factor MCM2

5

20

High-throughput

0.922

High

1381852

H2B1L
Histone H2B type 1-L

5

20

High-throughput

0.922

High

1109968

HDAC1
Histone deacetylase 1

4

20

Small-scale

0.899

High

502088

H2AZ
Histone H2A.Z

4

20

High-throughput

0.895

High

502468

H2A1
Histone H2A type 1

4

20

High-throughput

0.895

High

320350

PHF14
PHD finger protein 14

4

20

High-throughput

0.892

High

1155314

VPS72
Vacuolar protein sorting-associated protein 72 homolog

4

6

High-throughput

0.892

High

1253863

SRCAP
Helicase SRCAP

4

20

High-throughput

0.892

High

1348740

BAHD1
Bromo adjacent homology domain-containing 1 protein

4

7

High-throughput

0.892

High

1371225

KAT5
Histone acetyltransferase KAT5

4

18

High-throughput

0.892

High

1381844

EP400
E1A-binding protein p400

4

20

High-throughput

0.892

High

449770

H2B1J
Histone H2B type 1-J

4

20

High-throughput

0.886

High

1368037

HDAC2
Histone deacetylase 2

3

20

Small-scale

0.866

High

277770

H2AY
Core histone macro-H2A.1

3

20

High-throughput

0.861

High

649387

H1T
Histone H1t

3

20

High-throughput

0.861

High

936830

NP1L1
Nucleosome assembly protein 1-like 1

3

18

High-throughput

0.861

High

1065347

SSRP1
FACT complex subunit SSRP1

3

20

High-throughput

0.861

High

1127748

HLTF
Helicase-like transcription factor

3

20

High-throughput

0.861

High

1307292

H2A2B
Histone H2A type 2-B

3

20

High-throughput

0.861

High

1381843

EHMT2
Histone-lysine N-methyltransferase EHMT2

3

10

High-throughput

0.861

High

1381845

IPO9
Importin-9

3

14

High-throughput

0.861

High

1381855

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

3

3

High-throughput

0.861

High

1381875

H2AW
Core histone macro-H2A.2

3

20

High-throughput

0.861

High

1381884

CDYL
Chromodomain Y-like protein

3

10

High-throughput

0.861

High

1381887

SP16H
FACT complex subunit SPT16

3

7

High-throughput

0.861

High

1162859

H2A2C
Histone H2A type 2-C

3

20

Small-scale

0.840

High

1163124

H2B2E
Histone H2B type 2-E

3

20

High-throughput

0.839

High

980103

H4
Histone H4

3

20

High-throughput

0.827

High

1381850

NP1L4
Nucleosome assembly protein 1-like 4

2

19

High-throughput

0.811

High

1381865

EHMT1
Histone-lysine N-methyltransferase EHMT1

2

9

High-throughput

0.789

High

256946

H2B1K
Histone H2B type 1-K

2

20

High-throughput

0.754

High

943401

H2BFS
Histone H2B type F-S

2

19

High-throughput

0.754

High

946852

H2B1D
Histone H2B type 1-D

2

20

High-throughput

0.754

High

987151

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

20

High-throughput

0.754

High

987439

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

2

20

High-throughput

0.754

High

1372256

H2B1H
Histone H2B type 1-H

2

19

High-throughput

0.754

High

1381886

TRRAP
Transformation/transcription domain-associated protein

5

6

High-throughput

0.712

High

1381867

CBX8
Chromobox protein homolog 8

1

20

High-throughput

0.691

High

187151

PPM1G
Protein phosphatase 1G

4

11

High-throughput

0.691

High

340379

YETS4
YEATS domain-containing protein 4

4

8

High-throughput

0.691

High

1198107

EPC2
Enhancer of polycomb homolog 2

4

7

High-throughput

0.691

High

1277270

MIER3
Mesoderm induction early response protein 3

4

13

High-throughput

0.691

High

1322542

MIER1
Mesoderm induction early response protein 1

4

13

High-throughput

0.691

High

1381842

TONSL
Tonsoku-like protein

4

11

High-throughput

0.691

High

1381854

AN32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E

4

8

High-throughput

0.691

High

1381856

ARP6
Actin-related protein 6

4

7

High-throughput

0.691

High

1381858

BRD8
Bromodomain-containing protein 8

4

20

High-throughput

0.691

High

1381859

EPC1
Enhancer of polycomb homolog 1

4

7

High-throughput

0.691

High

1381866

EAF6
Chromatin modification-related protein MEAF6

4

4

High-throughput

0.691

High

1381868

HM20A
High mobility group protein 20A

4

20

High-throughput

0.691

High

1381869

DMAP1
DNA methyltransferase 1-associated protein 1

4

3

High-throughput

0.691

High

1381880

TCF20
Transcription factor 20

4

20

High-throughput

0.691

High

211658

ZNHI1
Zinc finger HIT domain-containing protein 1

3

2

High-throughput

0.667

High

317359

ACL6B
Actin-like protein 6B

3

9

High-throughput

0.667

High

355272

ACL6A
Actin-like protein 6A

3

9

High-throughput

0.667

High

755765

MCM4
DNA replication licensing factor MCM4

3

20

High-throughput

0.667

High

756296

MCM7
DNA replication licensing factor MCM7

3

20

High-throughput

0.667

High

832933

CETN2
Centrin-2

3

3

High-throughput

0.667

High

892601

DNLI3
DNA ligase 3

3

4

High-throughput

0.667

High

1032845

XPC
DNA repair protein complementing XP-C cells

3

6

High-throughput

0.667

High

1053304

MBTD1
MBT domain-containing protein 1

3

17

High-throughput

0.667

High

1128254

MCM6
DNA replication licensing factor MCM6

3

20

High-throughput

0.667

High

1133270

ARI5B
AT-rich interactive domain-containing protein 5B

3

18

High-throughput

0.667

High

1187982

GON4L
GON-4-like protein

3

3

High-throughput

0.667

High

1253822

MMS22
Protein MMS22-like

3

3

High-throughput

0.667

High

1309435

APLF
Aprataxin and PNK-like factor

3

1

High-throughput

0.667

High

1357714

TRI41
E3 ubiquitin-protein ligase TRIM41

3

4

High-throughput

0.667

High

1381846

CRML
Protein cramped-like

3

2

High-throughput

0.667

High

1381872

MRGBP
MRG/MORF4L-binding protein

3

2

High-throughput

0.667

High

1381873

TEX10
Testis-expressed protein 10

3

2

High-throughput

0.667

High

1381874

ING3
Inhibitor of growth protein 3

3

14

High-throughput

0.667

High

1381876

MO4L1
Mortality factor 4-like protein 1

3

8

High-throughput

0.667

High

1381879

PARP2
Poly [ADP-ribose] polymerase 2

3

17

High-throughput

0.667

High

1381883

RUVB2
RuvB-like 2

3

13

High-throughput

0.667

High

1381885

RUVB1
RuvB-like 1

3

13

High-throughput

0.667

High

487615

PARP1
Poly [ADP-ribose] polymerase 1

3

20

Small-scale

0.660

High

188336

HDAC3
Histone deacetylase 3

1

20

Small-scale

0.647

High

990980

UBE2B
Ubiquitin-conjugating enzyme E2 B

1

7

Small-scale

0.647

High

1029354

SET
Protein SET

1

20

Small-scale

0.647

High

1291977

JAZF1
Juxtaposed with another zinc finger protein 1

3

0

High-throughput

0.634

High

1381877

CFDP1
Craniofacial development protein 1

4

5

High-throughput

0.630

High

189241

IPO8
Importin-8

1

14

High-throughput

0.618

High

419127

H2A1B
Histone H2A type 1-B/E

1

20

High-throughput

0.618

High

507302

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

20

High-throughput

0.618

High

508392

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

High-throughput

0.618

High

591770

H2AX
Histone H2AX

1

20

High-throughput

0.618

High

623474

RO52
E3 ubiquitin-protein ligase TRIM21

1

5

High-throughput

0.618

High

659930

H2B1O
Histone H2B type 1-O

1

20

High-throughput

0.618

High

754936

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.618

High

903227

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

20

High-throughput

0.618

High

980990

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.618

High

998649

H31
Histone H3.1

1

20

High-throughput

0.618

High

1132882

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.618

High

1161987

H31T
Histone H3.1t

1

20

High-throughput

0.618

High

1208868

H2B2F
Histone H2B type 2-F

1

20

High-throughput

0.618

High

1258906

H32
Histone H3.2

1

20

High-throughput

0.618

High

1259622

H2AV
Histone H2A.V

1

20

High-throughput

0.618

High

1292498

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

1

20

High-throughput

0.618

High

1372234

H2A1C
Histone H2A type 1-C

1

20

High-throughput

0.618

High

1381851

H2B1N
Histone H2B type 1-N

1

20

High-throughput

0.618

High

617718

XRCC1
DNA repair protein XRCC1

2

2

High-throughput

0.611

High

1136831

MO4L2
Mortality factor 4-like protein 2

2

8

High-throughput

0.611

High

1358818

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

2

High-throughput

0.611

High

1381861

SENP3
Sentrin-specific protease 3

2

4

High-throughput

0.611

High

1244441

CP087
UPF0547 protein C16orf87

3

2

High-throughput

0.609

High

426549

HMGN2
Non-histone chromosomal protein HMG-17

2

20

High-throughput

0.584

High

1198195

PDCD4
Programmed cell death protein 4

2

8

High-throughput

0.584

High

1216233

H37
Histone H3-7

1

20

High-throughput

0.575

High

1381848

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

20

High-throughput

0.575

High

702365

ELK4
ETS domain-containing protein Elk-4

2

12

High-throughput

0.571

High

1380576

IGSF8
Immunoglobulin superfamily member 8

1

20

High-throughput

0.553

High

340925

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

18

High-throughput

0.536

High

471165

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.536

High

593181

CREB1
Cyclic AMP-responsive element-binding protein 1

1

2

High-throughput

0.536

High

1034695

MEF2A
Myocyte-specific enhancer factor 2A

1

1

High-throughput

0.536

High

1270593

COX15
Heme A synthase COX15

1

2

High-throughput

0.536

High

1381853

PSF3
DNA replication complex GINS protein PSF3

1

1

High-throughput

0.536

High

422804

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

1007651

CCNA1
Cyclin-A1

1

1

Small-scale

0.501

High

1208792

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

2

Small-scale

0.501

High

1366735

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

9

Small-scale

0.501

High

1381857

UBP44
Ubiquitin carboxyl-terminal hydrolase 44

1

20

Small-scale

0.501

High

137469

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

20

High-throughput

0.479

High

138263

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

13

High-throughput

0.479

High

214893

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

3

High-throughput

0.479

High

223241

PRC1
Protein regulator of cytokinesis 1

1

9

High-throughput

0.479

High

250753

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

3

High-throughput

0.479

High

315848

RECQ4
ATP-dependent DNA helicase Q4

1

14

High-throughput

0.479

High

325035

HEXI1
Protein HEXIM1

1

14

High-throughput

0.479

High

331215

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

424445

HMGN1
Non-histone chromosomal protein HMG-14

1

8

High-throughput

0.479

High

427922

ICAM1
Intercellular adhesion molecule 1

1

20

High-throughput

0.479

High

468670

HS90B
Heat shock protein HSP 90-beta

1

5

High-throughput

0.479

High

558314

XRCC6
X-ray repair cross-complementing protein 6

1

8

High-throughput

0.479

High

601801

HMGA1
High mobility group protein HMG-I/HMG-Y

1

15

High-throughput

0.479

High

651698

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

16

Small-scale

0.479

High

658324

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

756003

MCM5
DNA replication licensing factor MCM5

1

20

High-throughput

0.479

High

831193

CCNF
Cyclin-F

1

7

High-throughput

0.479

High

875745

PRC2A
Protein PRRC2A

1

20

High-throughput

0.479

High

897931

CDK9
Cyclin-dependent kinase 9

1

20

High-throughput

0.479

High

959895

RS3A
Small ribosomal subunit protein eS1

1

2

High-throughput

0.479

High

977324

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

High-throughput

0.479

High

981627

RAN
GTP-binding nuclear protein Ran

1

6

High-throughput

0.479

High

1027648

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

8

High-throughput

0.479

High

1035828

KIF23
Kinesin-like protein KIF23

1

20

High-throughput

0.479

High

1127062

RBM39
RNA-binding protein 39

1

5

High-throughput

0.479

High

1137441

SUZ12
Polycomb protein SUZ12

1

3

High-throughput

0.479

High

1140663

KIF14
Kinesin-like protein KIF14

1

16

High-throughput

0.479

High

1151428

HMGN3
High mobility group nucleosome-binding domain-containing protein 3

1

14

High-throughput

0.479

High

1194266

LARP7
La-related protein 7

1

20

High-throughput

0.479

High

1271776

MEPCE
7SK snRNA methylphosphate capping enzyme

1

14

High-throughput

0.479

High

1313318

SMC5
Structural maintenance of chromosomes protein 5

1

14

High-throughput

0.479

High

1314670

SRRM1
Serine/arginine repetitive matrix protein 1

1

20

High-throughput

0.479

High

1316568

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

20

High-throughput

0.479

High

1334730

SERB1
SERPINE1 mRNA-binding protein 1

1

12

High-throughput

0.479

High

1361664

ELYS
Protein ELYS

1

20

High-throughput

0.479

High

1381841

AURKB
Aurora kinase B

1

19

High-throughput

0.479

High

1381847

IWS1
Protein IWS1 homolog

1

20

High-throughput

0.479

High

1381860

CHM4B
Charged multivesicular body protein 4b

1

9

High-throughput

0.479

High

1381862

PGES2
Prostaglandin E synthase 2

1

2

High-throughput

0.479

High

1381864

ECT2
Protein ECT2

1

4

High-throughput

0.479

High

1381870

BRD7
Bromodomain-containing protein 7

1

20

Small-scale

0.479

High

1381871

ANLN
Anillin

1

3

High-throughput

0.479

High

1381882

TENN
Tenascin-N

1

20

High-throughput

0.479

High

430209

JUN
Transcription factor Jun

1

10

High-throughput

0.445

High

626320

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

3

High-throughput

0.445

High

1157668

CRY1
Cryptochrome-1

1

3

Small-scale

0.445

High

1381863

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

1

High-throughput

0.445

High

1381881

SMBT1
Scm-like with four MBT domains protein 1

1

20

Small-scale

0.445

High

136955

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

2

High-throughput

0.437

High

157709

CTRO
Citron Rho-interacting kinase

1

17

High-throughput

0.437

High

258169

IF2P
Eukaryotic translation initiation factor 5B

1

3

High-throughput

0.437

High

460608

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

8

High-throughput

0.437

High

663437

RIR1
Ribonucleoside-diphosphate reductase large subunit

1

2

High-throughput

0.437

High

867811

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

7

High-throughput

0.437

High

948903

CD81
CD81 antigen

1

11

High-throughput

0.437

High

1254952

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.437

High

1257746

VP13C
Intermembrane lipid transfer protein VPS13C

1

2

High-throughput

0.437

High

1323605

LRC47
Leucine-rich repeat-containing protein 47

1

1

High-throughput

0.437

High

1324036

RHG24
Rho GTPase-activating protein 24

1

15

High-throughput

0.437

High

1381849

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

2

High-throughput

0.437

High

1381878

ABCF2
ATP-binding cassette sub-family F member 2

1

8

High-throughput

0.437

High

1381888

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

4

High-throughput

0.437

High

1258660

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025