HitPredict

Interactor 1: NEB2 (Q6R891)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: Ppp1r9b

Interactor 2: PCLO (Q9QYX7)
Protein piccolo (Aczonin) (Brain-derived HLMN protein) (Multidomain presynaptic cytomatrix protein)
Gene: PCLO

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28634551
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~PDZ, PDZ~PDZ_5
Common GO terms	GO:0014069 - postsynaptic density GO:0030425 - dendrite GO:0030426 - growth cone GO:0043025 - neuronal cell body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 817 Mm			1 5068
+	Mm
		292195 NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00		BSN_MOUSE (1-3264): 4.89e-31: 138: 8.98
+	Mm
		802301 NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00		SYT1_MOUSE (4762-5064): 4.7e-31: 131: 14.97
+	Mm
		1164096 NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00		SYT7_MOUSE (4747-5066): 5.96e-30: 128: 16.27
+	Mm
		1163989 NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00		ANK2_MOUSE (24-2104): 4.59e-21: 105: 10.37
+	Mm
		934629 NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00		KPCB_MOUSE (4624-4758): 6.23e-14: 80.9: 36.30
+	Mm
		930568 NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00		KPCG_MOUSE (4624-4758): 4.72e-13: 78.2: 36.96
+	Mm
		581225 NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00		NFH_MOUSE (855-1475): 3.09e-10: 69.2: 15.07
+	Rn
		404390 DLG3_RAT (224-734): 2.62e-39: 158: 16.04		KPCA_RAT (4938-5061): 4.66e-29: 129: 24.60
+	Hs
		566427 LNX2_HUMAN (73-580): 2.53e-36: 148: 12.26		KPCA_HUMAN (4938-5061): 3.55e-29: 129: 24.60
+	Hs
		566437 LNX1_HUMAN (224-773): 4.36e-33: 138: 11.92		KPCA_HUMAN (4938-5061): 3.55e-29: 129: 24.60
+	Mm
		802298 DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04		SYT1_MOUSE (4762-5064): 4.7e-31: 131: 14.97
+	Ce
		103468 DLG1_CAEEL (45-815): 3.37e-50: 192: 12.38		TTN1_CAEEL (1885-2413): 8.06e-10: 68.3: 12.55
+	Rn
		404387 DLG4_RAT (438-714): 2.14e-29: 127: 16.03		KPCA_RAT (4938-5061): 4.66e-29: 129: 24.60
+	Hs
		566353 DLG4_HUMAN (438-714): 1.14e-29: 127: 16.03		KPCA_HUMAN (4938-5061): 3.55e-29: 129: 24.60
+	Mm
		1143421 DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04		ANK2_MOUSE (24-2104): 4.59e-21: 105: 10.37
+	Hs
		297818 AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69		K0754_HUMAN (1295-1889): 3.39e-12: 76: 11.02
+	Mm
		934625 DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04		KPCB_MOUSE (4624-4758): 6.23e-14: 80.9: 36.30
+	Mm
		930567 DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04		KPCG_MOUSE (4624-4758): 4.72e-13: 78.2: 36.96
+	Mm
		250607 LNX1_MOUSE (224-773): 2.22e-30: 130: 12.21		KPCG_MOUSE (4624-4758): 4.72e-13: 78.2: 36.96
+	Mm
		581224 DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04		NFH_MOUSE (855-1475): 3.09e-10: 69.2: 15.07