Protein: PTPRM
Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48)

Gene: PTPRM
Organism: Homo sapiens
Interactions: 66
UniProt ID: P28827

Gene Ontology (top 5):
GO:0001937 - negative regulation of endothelial cell proliferation
GO:0004725 - protein tyrosine phosphatase activity
GO:0005001 - transmembrane receptor protein tyrosine phosphatase activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

705697

RACK1
Small ribosomal subunit protein RACK1

2

0

Small-scale

0.773

High

705682

PTPRM
Receptor-type tyrosine-protein phosphatase mu

2

16

Small-scale

0.745

High

705686

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

4

Small-scale

0.647

High

374419

RASH
GTPase HRas

1

10

High-throughput

0.618

High

375207

RASK
GTPase KRas

1

15

High-throughput

0.618

High

610998

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

17

High-throughput

0.618

High

705683

EPHA2
Ephrin type-A receptor 2

1

10

High-throughput

0.618

High

705684

MUC18
Cell surface glycoprotein MUC18

1

13

High-throughput

0.618

High

705685

BAG6
Large proline-rich protein BAG6

1

2

High-throughput

0.618

High

705695

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

705696

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

705702

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

17

High-throughput

0.618

High

705707

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

2

High-throughput

0.618

High

705712

LMTK2
Serine/threonine-protein kinase LMTK2

1

20

High-throughput

0.618

High

555891

CADH1
Cadherin-1

2

20

Small-scale

0.584

High

439963

LCK
Tyrosine-protein kinase Lck

1

20

High-throughput

0.575

High

254061

CTND1
Catenin delta-1

1

20

Small-scale

0.561

High

705699

GANAB
Neutral alpha-glucosidase AB

1

4

High-throughput

0.553

High

705720

CNKR1
Connector enhancer of kinase suppressor of ras 1

1

5

Small-scale

0.501

High

705722

DTBP1
Dysbindin

1

0

High-throughput

0.493

High

128159

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

5

High-throughput

0.479

High

172492

XPO1
Exportin-1

1

14

High-throughput

0.479

High

173866

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

3

High-throughput

0.479

High

705692

XPO2
Exportin-2

1

14

High-throughput

0.479

High

705693

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

705700

PDIA6
Protein disulfide-isomerase A6

1

13

High-throughput

0.479

High

705708

GET4
Golgi to ER traffic protein 4 homolog

1

1

High-throughput

0.479

High

705710

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.479

High

705716

CIP2A
Protein CIP2A

1

2

High-throughput

0.479

High

705718

GCN1
Stalled ribosome sensor GCN1

1

9

High-throughput

0.479

High

705719

TNPO1
Transportin-1

1

10

High-throughput

0.479

High

705726

UN45A
Protein unc-45 homolog A

1

2

High-throughput

0.479

High

705731

ATX10
Ataxin-10

1

1

High-throughput

0.479

High

705733

AMFR
E3 ubiquitin-protein ligase AMFR

1

12

High-throughput

0.479

High

705694

H2B1D
Histone H2B type 1-D

1

2

High-throughput

0.470

High

705704

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.470

High

705711

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.458

High

705715

TBC15
TBC1 domain family member 15

1

0

High-throughput

0.458

High

705723

WRIP1
ATPase WRNIP1

1

0

High-throughput

0.458

High

705725

EHD4
EH domain-containing protein 4

1

0

High-throughput

0.458

High

480719

LEG1
Galectin-1

1

20

High-throughput

0.445

High

705714

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

3

High-throughput

0.445

High

705732

FBX2
F-box only protein 2

1

9

High-throughput

0.445

High

127889

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

5

High-throughput

0.437

High

698403

CALX
Calnexin

1

8

High-throughput

0.437

High

705688

LMAN1
Protein ERGIC-53

1

2

High-throughput

0.437

High

705690

KIF11
Kinesin-like protein KIF11

1

1

High-throughput

0.437

High

705691

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

1

High-throughput

0.437

High

705701

NOMO1
BOS complex subunit NOMO1

1

2

High-throughput

0.437

High

705703

UBE3C
Ubiquitin-protein ligase E3C

1

4

High-throughput

0.437

High

705706

NHSL1
NHS-like protein 1

1

6

High-throughput

0.437

High

705709

MON2
Protein MON2 homolog

1

2

High-throughput

0.437

High

705713

DJC10
DnaJ homolog subfamily C member 10

1

19

High-throughput

0.437

High

705717

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

4

High-throughput

0.437

High

705724

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

4

High-throughput

0.437

High

705727

ATD3A
ATPase family AAA domain-containing protein 3A

1

4

High-throughput

0.437

High

705729

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

3

High-throughput

0.437

High

705734

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

2

High-throughput

0.437

High

705721

SAAL1
Protein SAAL1

1

4

High-throughput

0.407

High

705730

BCCIP
BRCA2 and CDKN1A-interacting protein

1

0

Small-scale

0.286

High

705698

SBP1
Methanethiol oxidase

1

0

High-throughput

0.269

Low

705687

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

0

High-throughput

0.249

Low

705689

MSH6
DNA mismatch repair protein Msh6

1

0

High-throughput

0.249

Low

705705

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.249

Low

705728

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025