Interactor 1: TRXR1 (Q16881)
Thioredoxin reductase 1, cytoplasmic (TR) (EC 1.8.1.9) (Gene associated with retinoic and interferon-induced mortality 12 protein) (GRIM-12) (Gene associated with retinoic and IFN-induced mortality 12 protein) (KM-102-derived reductase-like factor) (Peroxidase TXNRD1) (EC 1.11.1.2) (Thioredoxin reductase TR1)
Gene: TXNRD1
Interactor 2: GLRX2 (Q9NS18)
Glutaredoxin-2, mitochondrial
Gene: GLRX2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 14676218 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Glutaredoxin~Glutaredoxin, Glutaredoxin~Pyr_redox_2 |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0045454 - cell redox homeostasis |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
