HitPredict

Interactor 1: CPEB4 (Q17RY0)
Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4)
Gene: CPEB4

Interactor 2: AGO1 (Q9UL18)
Protein argonaute-1 (Argonaute1) (hAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99)
Gene: AGO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 729 Hs			1 857
+	Hs
		1165524 CPEB4_HUMAN (1-729): 0: 722: 100.00		AGO2_HUMAN (19-857): 0: 1192: 83.43
+	Hs
		1165507 CPEB4_HUMAN (1-729): 0: 722: 100.00		AGO3_HUMAN (1-857): 0: 1177: 83.83
+	Hs
		1419553 CPEB1_HUMAN (449-720): 5.48e-66: 230: 40.42		AGO1_HUMAN (1-857): 0: 1208: 100.00
+	Hs
		1419551 CPEB1_HUMAN (449-720): 5.48e-66: 230: 40.42		AGO2_HUMAN (19-857): 0: 1192: 83.43
+	Hs
		1419537 CPEB1_HUMAN (449-720): 5.48e-66: 230: 40.42		AGO3_HUMAN (1-857): 0: 1177: 83.83
+	Mm
		1298791 Q99LF8_MOUSE (356-673): 4.43e-45: 173: 11.22		AGO2_MOUSE (3-857): 0: 1199: 82.36
+	Hs
		550515 PABP1_HUMAN (463-673): 1.1e-31: 133: 17.54		AGO1_HUMAN (1-857): 0: 1208: 100.00
+	Hs
		1102105 PABP4_HUMAN (356-673): 1.94e-47: 180: 11.53		AGO4_HUMAN (9-857): 0: 1155: 83.04
+	Hs
		1432513 PABP3_HUMAN (463-673): 7.43e-30: 127: 17.06		AGO1_HUMAN (1-857): 0: 1208: 100.00
+	Mm
		710999 PABP1_MOUSE (463-673): 1.27e-31: 133: 17.54		AGO2_MOUSE (3-857): 0: 1199: 82.36
+	Hs
		550513 PABP1_HUMAN (463-673): 1.1e-31: 133: 17.54		AGO2_HUMAN (19-857): 0: 1192: 83.43
+	Hs
		550470 PABP1_HUMAN (463-673): 1.1e-31: 133: 17.54		AGO3_HUMAN (1-857): 0: 1177: 83.83
+	Hs
		550476 PABP1_HUMAN (463-673): 1.1e-31: 133: 17.54		AGO4_HUMAN (9-857): 0: 1155: 83.04
+	Ce
		114175 Q19581_CAEEL (452-726): 4.72e-30: 127: 15.55		G5EGR6_CAEEL (21-857): 0: 1098: 66.36
+	Ce
		113514 MSI1H_CAEEL (571-668): 1.21e-21: 98.4: 22.45		G5EGR6_CAEEL (21-857): 0: 1098: 66.36
+	Zm
		9917 A0A1D6EZQ5_MAIZE (578-681): 1.64e-21: 100: 24.04		A0A1D6FB88_MAIZE (9-856): 0: 863: 29.31
+	Dm
		304504 PABP_DROME (363-673): 1.52e-42: 165: 14.33		AUB_DROME (2-815): 0: 603: 21.71