Protein: AGO2
Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer)

Gene: AGO2
Organism: Mus musculus
Interactions: 59
UniProt ID: Q8CJG0

Gene Ontology (top 5):
GO:0000340 - RNA 7-methylguanosine cap binding
GO:0000932 - P-body
GO:0000993 - RNA polymerase II complex binding
GO:0001046 - core promoter sequence-specific DNA binding
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1223069

FXR1
RNA-binding protein FXR1

2

15

Small-scale

0.601

High

266614

DHX9
ATP-dependent RNA helicase A

1

12

Small-scale

0.575

High

1021520

TRBP2
RISC-loading complex subunit TARBP2

1

16

Small-scale

0.575

High

1298783

AGO3
Protein argonaute-3

1

12

Small-scale

0.575

High

1298787

DICER
Endoribonuclease Dicer

1

20

Small-scale

0.575

High

1190094

TNR6C
Trinucleotide repeat-containing gene 6C protein

2

17

Small-scale

0.571

High

1296906

TNR6B
Trinucleotide repeat-containing gene 6B protein

2

18

Small-scale

0.571

High

1169404

LIN41
E3 ubiquitin-protein ligase TRIM71

1

16

Small-scale

0.561

High

710999

PABP1
Polyadenylate-binding protein 1

2

9

Small-scale

0.552

High

1000313

ELAV1
ELAV-like protein 1

2

13

Small-scale

0.552

High

1190266

TNR6A
Trinucleotide repeat-containing gene 6A protein

2

17

Small-scale

0.552

High

1240111

HDAC4
Histone deacetylase 4

1

4

High-throughput

0.536

High

1298053

PEX5R
PEX5-related protein

1

3

High-throughput

0.536

High

1197148

RC3H1
Roquin-1

1

4

Small-scale

0.515

High

1191128

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

1

High-throughput

0.479

High

1210218

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

1

High-throughput

0.479

High

1297158

Q8BPK8
Fragile X messenger ribonucleoprotein 1

1

15

High-throughput

0.479

High

1298792

TDRD1
Tudor domain-containing protein 1

1

20

Small-scale

0.479

High

1221772

SC6A4
Sodium-dependent serotonin transporter

1

0

High-throughput

0.458

High

99230

HERC6
E3 ISG15--protein ligase Herc6

1

3

Small-scale

0.445

High

312364

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

14

Small-scale

0.445

High

462139

HS90A
Heat shock protein HSP 90-alpha

1

20

Small-scale

0.445

High

616107

KS6A1
Ribosomal protein S6 kinase alpha-1

1

1

Small-scale

0.445

High

777970

FMR1
Fragile X messenger ribonucleoprotein 1

1

15

High-throughput

0.445

High

847001

H14
Histone H1.4

1

1

Small-scale

0.445

High

932550

DDX6
Probable ATP-dependent RNA helicase DDX6

1

19

Small-scale

0.445

High

972640

RS14
Small ribosomal subunit protein uS11

1

1

Small-scale

0.445

High

973020

RS18
Small ribosomal subunit protein uS13

1

4

Small-scale

0.445

High

986933

YBOX1
Y-box-binding protein 1

1

8

Small-scale

0.445

High

1021216

RS3A
Small ribosomal subunit protein eS1

1

3

Small-scale

0.445

High

1021475

RS5
Small ribosomal subunit protein uS7

1

4

Small-scale

0.445

High

1188032

Q3TA75
Agenet-like domain-containing protein

1

15

Small-scale

0.445

High

1189358

Q3TFC0
RNA helicase

1

10

Small-scale

0.445

High

1189938

Q3U6P5
RRM domain-containing protein

1

7

Small-scale

0.445

High

1190318

EDC4
Enhancer of mRNA-decapping protein 4

1

5

Small-scale

0.445

High

1208156

Q5M9P3
Small ribosomal subunit protein eS19

1

1

Small-scale

0.445

High

1209912

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

14

Small-scale

0.445

High

1221564

CNOT7
CCR4-NOT transcription complex subunit 7

1

6

Small-scale

0.445

High

1225715

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

13

Small-scale

0.445

High

1230082

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

4

Small-scale

0.445

High

1253445

LARP1
La-related protein 1

1

3

Small-scale

0.445

High

1259106

Q71LX8
Heat shock protein 84b

1

20

Small-scale

0.445

High

1281973

PUM2
Pumilio homolog 2

1

4

Small-scale

0.445

High

1298785

MATR3
Matrin-3

1

5

Small-scale

0.445

High

1298786

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

15

Small-scale

0.445

High

1298788

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

5

Small-scale

0.445

High

1298789

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

12

Small-scale

0.445

High

1298790

YTHD2
YTH domain-containing family protein 2

1

11

Small-scale

0.445

High

1298791

Q99LF8
Polyadenylate-binding protein

1

9

Small-scale

0.445

High

1298793

DHX30
ATP-dependent RNA helicase DHX30

1

12

Small-scale

0.445

High

1298794

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

14

Small-scale

0.445

High

1298795

RENT1
Regulator of nonsense transcripts 1

1

10

Small-scale

0.445

High

1298796

YBOX3
Y-box-binding protein 3

1

8

Small-scale

0.445

High

1298797

TEBP
Prostaglandin E synthase 3

1

10

Small-scale

0.445

High

1296103

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

1

High-throughput

0.437

High

148417

RO60
RNA-binding protein Ro60

1

0

Small-scale

0.426

High

1189343

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

Small-scale

0.426

High

1211308

Q5SXR6
Clathrin heavy chain

1

0

Small-scale

0.426

High

1235606

ZN521
Zinc finger protein 521

1

0

Small-scale

0.426

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025