HitPredict

Interactor 1: SYNE3 (Q6ZMZ3)
Nesprin-3 (KASH domain-containing protein 3) (KASH3) (Nuclear envelope spectrin repeat protein 3)
Gene: SYNE3

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 975 Hs			1 1164
+	Hs
		1012563 SYNE3_HUMAN (1-975): 1.69e-66: 243: 100.00		CGNL1_HUMAN (280-1054): 5.93e-34: 144: 11.22
+	Hs
		969597 SYNE3_HUMAN (1-975): 1.69e-66: 243: 100.00		CENPE_HUMAN (620-984): 9.03e-10: 65.5: 20.36
+	Hs
		725097 MYH10_HUMAN (1-826): 4.57e-32: 138: 11.81		MYH11_HUMAN (392-1122): 2.73e-28: 126: 8.64
+	Hs
		724687 MYH10_HUMAN (1-826): 4.57e-32: 138: 11.81		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		148461 MYH10_HUMAN (1-826): 4.57e-32: 138: 11.81		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		528395 MYH6_HUMAN (299-923): 8.86e-20: 98: 10.57		CACO1_HUMAN (620-1116): 8.08e-29: 126: 14.93
+	Hs
		724943 MYH9_HUMAN (2-697): 2.15e-22: 106: 9.04		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		724686 MYH9_HUMAN (2-697): 2.15e-22: 106: 9.04		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		148460 MYH9_HUMAN (2-697): 2.15e-22: 106: 9.04		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		725174 MYH10_HUMAN (1-826): 4.57e-32: 138: 11.81		CYTSB_HUMAN (740-1117): 1.86e-12: 74.1: 12.41
+	Hs
		725189 MYH10_HUMAN (1-826): 4.57e-32: 138: 11.81		MYH14_HUMAN (620-918): 1.78e-11: 71.1: 13.11
+	Hs
		725095 MYH10_HUMAN (1-826): 4.57e-32: 138: 11.81		MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43
+	Mm
		93541 SPTA1_MOUSE (124-876): 2.06e-27: 122: 12.94		DESP_MOUSE (718-1164): 2.9e-13: 77.2: 10.89
+	Hs
		528356 MYH6_HUMAN (299-923): 8.86e-20: 98: 10.57		MYH6_HUMAN (623-1102): 9.65e-21: 101: 14.55
+	Hs
		724810 MYH9_HUMAN (2-697): 2.15e-22: 106: 9.04		ROCK1_HUMAN (433-926): 6.18e-15: 82.2: 12.00
+	Hs
		724861 MYH9_HUMAN (2-697): 2.15e-22: 106: 9.04		CYTSB_HUMAN (740-1117): 1.86e-12: 74.1: 12.41
+	Hs
		724895 MYH9_HUMAN (2-697): 2.15e-22: 106: 9.04		MYH14_HUMAN (620-918): 1.78e-11: 71.1: 13.11
+	Hs
		502901 MYH6_HUMAN (299-923): 8.86e-20: 98: 10.57		MYH3_HUMAN (400-850): 1.77e-10: 67.9: 10.00
+	Dm
		527109 SPTCA_DROME (399-876): 2.26e-20: 100: 11.81		Q9VCC9_DROME (835-1160): 2.53e-09: 63.7: 9.76