HitPredict

Interactor 1: SLY1 (Q24179)
Protein sly1 homolog
Gene: Slh

Interactor 2: Q9VVX6 (Q9VVX6)
BET1 homolog (Golgi vesicular membrane-trafficking protein p18)
Gene: Bet1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~Sec1
Common GO terms	GO:0000139 - Golgi membrane GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0016192 - vesicle-mediated transport GO:0019905 - syntaxin binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 639 Dm			1 117
+	Hs
		179995 SCFD1_HUMAN (3-631): 0: 561: 56.90		BET1_HUMAN (10-117): 1.08e-36: 122: 39.82
+	Hs
		1358381 SCFD1_HUMAN (3-631): 0: 561: 56.90		BET1L_HUMAN (20-114): 3.44e-24: 90.5: 31.25
+	Hs
		249885 SCFD1_HUMAN (3-631): 0: 561: 56.90		STX10_HUMAN (18-100): 5.6e-21: 85.9: 20.48
+	Hs
		226152 SCFD1_HUMAN (3-631): 0: 561: 56.90		STX6_HUMAN (8-100): 1.41e-19: 82.4: 22.58
+	Hs
		180064 VPS45_HUMAN (27-638): 6.62e-149: 444: 20.97		BET1_HUMAN (10-117): 1.08e-36: 122: 39.82
+	Sc
		646174 SLY1_YEAST (2-634): 4.28e-155: 463: 32.08		BET1_YEAST (17-114): 7.25e-25: 93.2: 21.43
+	Sc
		646192 SLY1_YEAST (2-634): 4.28e-155: 463: 32.08		SFT1_YEAST (19-116): 2.56e-21: 82.8: 19.39
+	Hs
		249900 VPS45_HUMAN (27-638): 6.62e-149: 444: 20.97		STX10_HUMAN (18-100): 5.6e-21: 85.9: 20.48
+	Hs
		226221 VPS45_HUMAN (27-638): 6.62e-149: 444: 20.97		STX6_HUMAN (8-100): 1.41e-19: 82.4: 22.58
+	Hs
		226196 VP33B_HUMAN (30-628): 2.62e-115: 359: 14.11		STX6_HUMAN (8-100): 1.41e-19: 82.4: 22.58