Interactor 1: PLPL7 (Q6ZV29)
Patatin-like phospholipase domain-containing protein 7 (EC 3.1.1.-) (EC 3.1.1.5)
Gene: PNPLA7

Interactor 2: PLPL6 (Q8IY17)
Patatin-like phospholipase domain-containing protein 6 (EC 3.1.1.5) (Neuropathy target esterase)
Gene: PNPLA6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains cNMP_binding~cNMP_binding, Patatin~Patatin
Common GO terms GO:0004622 - lysophospholipase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0102545 - phosphatidyl phospholipase B activity
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1317
Hs

1 1375
+ Hs
+ Hs
+ Hs
+ Sc
+ Ce
+ Bt
+ Hs
+ Sp
+ Hs
+ Bt
+ Hs
+ Ce
+ Zm
+ Dm
+ Dm
+ Mm
+ Hs

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Last updated: 15 Jul 2024