Interactor 1: ESC (Q24338)
Polycomb protein esc (Protein extra sex combs)
Gene: ESC
Interactor 2: SUZ12 (Q9NJG9)
Polycomb protein Su(z)12 (Suppressor 12 of zeste protein)
Gene: Su(z)12
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.970 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12697833, 12408864, 24100017, 26063573, 29242288, 29070704, 25242320, 15896722, 15776017, 16537908 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | VEFS-Box~WD40 |
| Common GO terms | GO:0000785 - chromatin GO:0005634 - nucleus GO:0035097 - histone methyltransferase complex GO:0035098 - ESC/E(Z) complex GO:0140718 - facultative heterochromatin formation |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
