HitPredict - High confidence protein-protein interactions

Protein: Q9VKD5
Polycomb protein esc (Protein extra sex combs)

Gene: Q9VKD5, escl
Organism: Drosophila melanogaster
Interactions: 7
UniProt ID: Q9VKD5

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0031507 - heterochromatin formation
GO:0035098 - ESC/E(Z) complex
GO:0140718 - facultative heterochromatin formation

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
837332	EZ Histone-lysine N-methyltransferase E(z)	2	20	Small-scale	0.754	High
1173881	ESC Polycomb protein esc	1	17	Small-scale	0.618	High
1175611	CAF1 Chromatin assembly factor 1 p55 subunit	1	17	Small-scale	0.618	High
1445691	SUZ12 Polycomb protein Su(z)12	1	9	Small-scale	0.618	High
381735	H3 Histone H3	1	12	Small-scale	0.553	High
1374482	HDAC1 Histone deacetylase HDAC1	1	20	Small-scale	0.479	High
1174295	PCL Polycomb protein Pcl	1	20	Small-scale	0.437	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025