HitPredict

Interactor 1: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Interactor 2: H2A2B (Q8IUE6)
Histone H2A type 2-B (H2A-clustered histone 21)
Gene: H2AC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	34349018, 37071682, 30021884
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 130
+	Hs
		934946 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		H2A2B_HUMAN (1-130): 2.22e-71: 211: 100.00
+	Hs
		1086203 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		H2A2B_HUMAN (1-130): 2.22e-71: 211: 100.00
+	Hs
		935141 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		H2A1A_HUMAN (1-129): 1.95e-68: 203: 92.25
+	Hs
		391649 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		470336 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		934877 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		H2A2A_HUMAN (1-130): 5.07e-68: 202: 94.62
+	Hs
		935170 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		H2A1J_HUMAN (1-128): 6.6e-68: 202: 95.31
+	Hs
		1086182 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		H2A2A_HUMAN (1-130): 5.07e-68: 202: 94.62
+	Hs
		1086192 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		H2A3_HUMAN (1-130): 6.67e-68: 202: 94.62
+	Hs
		1086278 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		H2A1H_HUMAN (1-128): 7.7e-68: 202: 95.31
+	Hs
		1086293 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		H2A1J_HUMAN (1-128): 6.6e-68: 202: 95.31
+	Hs
		391723 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		470399 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		934815 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		H2A2C_HUMAN (1-127): 3.2e-67: 200: 96.06
+	Mm
		935458 H31_MOUSE (1-136): 1.98e-62: 189: 99.27		Q8CGP4_MOUSE (1-126): 5.48e-67: 200: 90.48
+	Hs
		391757 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		1086165 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		H2A2C_HUMAN (1-127): 3.2e-67: 200: 96.06
+	Hs
		555411 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94
+	Mm
		952264 H32_MOUSE (1-136): 3.73e-61: 186: 100.00		Q8CGP4_MOUSE (1-126): 5.48e-67: 200: 90.48
+	Hs
		555485 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94