Protein: CED3
Cell death protein 3 (EC 3.4.22.60) (Caspase ced-3) [Cleaved into: Cell death protein 3 subunit p17; Cell death protein 3 subunit p15; Cell death protein 3 subunit p13]

Gene: CED3, ced-3
Organism: Caenorhabditis elegans
Interactions: 86
UniProt ID: P42573

Gene Ontology (top 5):
GO:0004175 - endopeptidase activity
GO:0004197 - cysteine-type endopeptidase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

719677

CED4
Cell death protein 4

11

0

Small-scale

0.933

High

837000

CED9
Apoptosis regulator ced-9

7

0

Small-scale

0.914

High

840011

CNT1
Arf-GAP with ANK repeat and PH domain-containing protein cnt-1

2

1

Small-scale

0.806

High

839962

CED3
Cell death protein 3

2

19

Small-scale

0.777

High

111192

CSP3
Non-catalytic caspase homolog csp-3

1

17

Small-scale

0.761

High

603138

FEM1
Sex-determining protein fem-1

1

0

Small-scale

0.614

High

759516

DCR1
Endoribonuclease dcr-1

2

5

Small-scale

0.602

High

839973

LIN28
Protein lin-28

2

1

Small-scale

0.602

High

515953

ACT3
Actin-3

2

5

Small-scale

0.595

High

760155

TBA2
Tubulin alpha-2 chain

2

3

Small-scale

0.595

High

839968

TBB2
Tubulin beta-2 chain

2

3

Small-scale

0.595

High

839975

BNIP3
NIP3 homolog

2

0

Small-scale

0.559

High

110956

G5ECL3
Pre-RNA processing 21

1

4

Small-scale

0.553

High

111306

G5ED07
Protein disulfide-isomerase

2

3

Small-scale

0.543

High

840002

Q95QI6
ANK_REP_REGION domain-containing protein

1

0

Small-scale

0.517

High

111313

PAX5H
Paired box protein 5 homolog

1

2

Small-scale

0.501

High

195276

STIP1
Stress-induced-phosphoprotein 1

1

2

Small-scale

0.501

High

196038

CED8
Cell death abnormality protein 8

1

1

Small-scale

0.501

High

534395

ACT2
Actin-2

1

5

Small-scale

0.501

High

759359

ACON
Probable aconitate hydratase, mitochondrial

1

1

Small-scale

0.501

High

839984

14332
14-3-3-like protein 2

1

4

Small-scale

0.501

High

839994

Q22972
Peptidase A1 domain-containing protein

1

1

Small-scale

0.501

High

840006

Q9N384
Galectin

1

2

Small-scale

0.501

High

113610

GPMI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase

1

0

Small-scale

0.480

High

196452

O17759
transketolase

1

0

Small-scale

0.480

High

624591

MLR2
Myosin regulatory light chain 2

1

0

Small-scale

0.480

High

698082

CALR
Calreticulin

1

0

Small-scale

0.480

High

839964

ATPB
ATP synthase subunit beta, mitochondrial

1

0

Small-scale

0.480

High

839974

DI3L2
DIS3-like exonuclease 2

1

0

Small-scale

0.480

High

839982

Q19007
Nucleosome assembly protein 1-like 1

1

0

Small-scale

0.480

High

839985

LIN14
Protein lin-14

1

0

Small-scale

0.480

High

839990

UGT50
Putative UDP-glucuronosyltransferase ugt-50

1

0

Small-scale

0.480

High

840005

Q9N302
Long-chain-fatty-acid--CoA ligase

1

0

Small-scale

0.480

High

84485

B7WNA0
Pyruvate kinase

1

2

Small-scale

0.479

High

112996

STIM1
Stromal interaction molecule 1

1

1

Small-scale

0.479

High

556468

MYO2
Myosin-2

1

1

Small-scale

0.479

High

758697

PLK1
Serine/threonine-protein kinase plk-1

1

1

High-throughput

0.479

High

839963

CPR6
Cathepsin B-like cysteine proteinase 6

1

1

Small-scale

0.479

High

839970

UBR1
E3 ubiquitin-protein ligase ubr-1

1

2

Small-scale

0.479

High

839997

Q7KPP4
CRAL-TRIO domain-containing protein

1

4

Small-scale

0.479

High

839999

Q8IAA8
Calpain catalytic domain-containing protein

1

2

Small-scale

0.479

High

840003

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

1

Small-scale

0.479

High

759644

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

Small-scale

0.458

High

839972

P91457
RanBP2-type domain-containing protein

1

0

Small-scale

0.458

High

839976

GARS
Glycine--tRNA ligase

1

0

Small-scale

0.458

High

839977

GCP
Bifunctional glyoxylate cycle protein

1

0

Small-scale

0.458

High

839979

Q18437
C3H1-type domain-containing protein

1

0

Small-scale

0.458

High

839980

Q18599
Acetyl-CoA hydrolase

1

0

Small-scale

0.458

High

839998

Q8I4H6
Arginyl-tRNA--protein transferase 1

1

0

Small-scale

0.458

High

840009

Q9NAH3
GYF domain-containing protein

1

0

Small-scale

0.458

High

534401

ACT4
Actin-4

1

5

Small-scale

0.457

High

839969

P91020
NADP-dependent oxidoreductase domain-containing protein

1

2

Small-scale

0.457

High

839991

Q22352
NADP-dependent oxidoreductase domain-containing protein

1

2

Small-scale

0.457

High

839995

ACOHC
Cytoplasmic aconitate hydratase

1

1

Small-scale

0.457

High

840004

Q966C5
SET domain-containing protein

1

1

Small-scale

0.457

High

840010

VATA
V-type proton ATPase catalytic subunit A

1

1

Small-scale

0.457

High

840008

MAC1
Protein mac-1

1

4

Small-scale

0.445

High

840000

CED12
Cell death abnormality protein 12

1

0

Small-scale

0.438

High

72278

A9D0C6
WD_REPEATS_REGION domain-containing protein

1

1

Small-scale

0.437

High

109668

G5EBH7
Reticulocalbin-3

1

1

Small-scale

0.437

High

111842

NLTP2
Non-specific lipid-transfer protein-like 2

1

1

Small-scale

0.437

High

112459

G5EEF0
Plant Late Embryo Abundant

1

4

Small-scale

0.437

High

234064

O45543
Translation initiation factor IF-2

1

2

Small-scale

0.437

High

234298

O45815
Actin

1

6

Small-scale

0.437

High

432252

VIT2
Vitellogenin-2

1

1

Small-scale

0.437

High

438853

VIT5
Vitellogenin-5

1

1

Small-scale

0.437

High

839978

Q17796
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

1

Small-scale

0.437

High

839981

LAM2
Laminin-like protein lam-2

1

1

Small-scale

0.437

High

839983

Q19790
Dauer Up-Regulated

1

3

Small-scale

0.437

High

839988

PDE4
Probable 3',5'-cyclic-AMP phosphodiesterase pde-4

1

1

Small-scale

0.437

High

839989

RHO1
Ras-like GTP-binding protein rhoA

1

3

Small-scale

0.437

High

839996

HSR9
Protein hsr-9

1

4

Small-scale

0.437

High

840001

MBK1
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1

1

5

High-throughput

0.437

High

116076

H2L0M6
Calponin-like protein OV9M

1

0

Small-scale

0.261

Low

839965

TCPD
T-complex protein 1 subunit delta

1

0

Small-scale

0.261

Low

839967

RS12
Small ribosomal subunit protein eS12

1

0

Small-scale

0.261

Low

144744

O01524
SNU

1

0

Small-scale

0.249

Low

264330

SYQ
Probable glutamine--tRNA ligase

1

0

Small-scale

0.249

Low

839966

RS5
Small ribosomal subunit protein uS7

1

0

Small-scale

0.249

Low

839971

RRP15
RRP15-like protein

1

0

Small-scale

0.249

Low

839986

Q21650
Chitin-binding type-2 domain-containing protein

1

0

Small-scale

0.249

Low

839987

Q21816
VWFA domain-containing protein

1

0

Small-scale

0.249

Low

839992

Q22469
Matrin-type domain-containing protein

1

0

Small-scale

0.249

Low

839993

IF5
Eukaryotic translation initiation factor 5

1

0

Small-scale

0.249

Low

840007

Q9N5N3
SCP domain-containing protein

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025