HitPredict

Interactor 1: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Interactor 2: SET1B (Q9UPS6)
Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.364) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B)
Gene: SETD1B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	22266653
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~N-SET, Histone~SET
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 1966
+	Hs
		935374 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SET1B_HUMAN (1-1966): 3.57e-162: 549: 100.00
+	Hs
		935368 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KMT2B_HUMAN (1069-1966): 4.68e-71: 268: 21.69
+	Hs
		935205 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		NSD3_HUMAN (1721-1965): 3.64e-68: 256: 24.90
+	Hs
		934681 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KMT2A_HUMAN (1173-1966): 2.68e-66: 252: 21.73
+	Hs
		975268 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		KMT2A_HUMAN (1173-1966): 2.68e-66: 252: 21.73
+	Hs
		203659 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV91_HUMAN (1686-1965): 2.95e-70: 244: 17.93
+	Hs
		935237 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV92_HUMAN (1717-1966): 9.97e-68: 237: 20.29
+	Hs
		935276 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		ASH1L_HUMAN (181-1965): 1.4e-61: 236: 10.39
+	Hs
		934804 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		EZH2_HUMAN (1464-1949): 9.8e-64: 235: 15.84
+	Hs
		1079993 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		EZH2_HUMAN (1464-1949): 9.8e-64: 235: 15.84
+	Hs
		331780 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		NSD2_HUMAN (1654-1965): 6.33e-60: 230: 22.15
+	Hs
		331823 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		NSD2_HUMAN (1654-1965): 6.33e-60: 230: 22.15
+	Hs
		935004 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KMT2C_HUMAN (1759-1966): 1.32e-58: 227: 37.04
+	Hs
		1086228 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		KMT2C_HUMAN (1759-1966): 1.32e-58: 227: 37.04
+	Hs
		935204 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SETD2_HUMAN (1733-1965): 3.5e-58: 225: 24.07
+	Hs
		1086306 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		SETD2_HUMAN (1733-1965): 3.5e-58: 225: 24.07
+	Hs
		935129 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		NSD1_HUMAN (1721-1965): 2.24e-57: 223: 23.70
+	Hs
		1086280 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		NSD1_HUMAN (1721-1965): 2.24e-57: 223: 23.70
+	Hs
		165661 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SET1A_HUMAN (409-1966): 1e-54: 214: 22.13
+	Hs
		152625 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KMT2D_HUMAN (1826-1966): 3.07e-17: 91.3: 46.85