Protein: DLGP1
Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)

Gene: DLGP1, Dlgap1
Organism: Mus musculus
Interactions: 173
UniProt ID: Q9D415

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0007268 - chemical synaptic transmission
GO:0014069 - postsynaptic density
GO:0044877 - protein-containing complex binding
GO:0045202 - synapse

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

73171

DLGP4
Disks large-associated protein 4

2

6

High-throughput

0.789

High

92686

SHAN1
SH3 and multiple ankyrin repeat domains protein 1

2

19

High-throughput

0.789

High

1193934

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

20

High-throughput

0.789

High

1244247

DLGP3
Disks large-associated protein 3

2

6

High-throughput

0.789

High

1283096

SHAN2
SH3 and multiple ankyrin repeat domains protein 2

2

20

High-throughput

0.789

High

1296788

DLGP2
Disks large-associated protein 2

2

6

High-throughput

0.789

High

1223726

DLG4
Disks large homolog 4

5

20

High-throughput

0.706

High

104635

SYGP1
Ras/Rap GTPase-activating protein SynGAP

4

9

High-throughput

0.686

High

771505

NMDZ1
Glutamate receptor ionotropic, NMDA 1

3

12

High-throughput

0.667

High

1190202

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

3

7

High-throughput

0.667

High

1029244

NMDE2
Glutamate receptor ionotropic, NMDA 2B

3

12

High-throughput

0.660

High

663177

GRIA2
Glutamate receptor 2

3

7

High-throughput

0.656

High

1317442

DLGP5
Disks large-associated protein 5

1

6

High-throughput

0.618

High

148526

CYH3
Cytohesin-3

2

3

High-throughput

0.611

High

205687

CTND2
Catenin delta-2

2

4

High-throughput

0.611

High

236985

CNTP1
Contactin-associated protein 1

2

1

High-throughput

0.611

High

237190

SEPT7
Septin-7

2

4

High-throughput

0.611

High

595027

KCNA1
Potassium voltage-gated channel subfamily A member 1

2

2

High-throughput

0.611

High

619287

NFH
Neurofilament heavy polypeptide

2

1

High-throughput

0.611

High

704231

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

2

9

High-throughput

0.611

High

723745

CTND1
Catenin delta-1

2

5

High-throughput

0.611

High

771433

NMDE1
Glutamate receptor ionotropic, NMDA 2A

2

12

High-throughput

0.611

High

837998

SEPT2
Septin-2

2

4

High-throughput

0.611

High

873445

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

2

4

High-throughput

0.611

High

884994

CDK5
Cyclin-dependent kinase 5

2

1

High-throughput

0.611

High

972310

1433E
14-3-3 protein epsilon

2

1

High-throughput

0.611

High

982156

RAP1A
Ras-related protein Rap-1A

2

4

High-throughput

0.611

High

983643

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

2

1

High-throughput

0.611

High

984362

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

2

1

High-throughput

0.611

High

988912

RAC1
Ras-related C3 botulinum toxin substrate 1

2

1

High-throughput

0.611

High

989585

MK01
Mitogen-activated protein kinase 1

2

1

High-throughput

0.611

High

989703

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

2

5

High-throughput

0.611

High

990947

KCNA2
Potassium voltage-gated channel subfamily A member 2

2

2

High-throughput

0.611

High

993947

KPCG
Protein kinase C gamma type

2

1

High-throughput

0.611

High

996086

RACK1
Small ribosomal subunit protein RACK1

2

1

High-throughput

0.611

High

996633

1433T
14-3-3 protein theta

2

6

High-throughput

0.611

High

998189

KPCB
Protein kinase C beta type

2

1

High-throughput

0.611

High

999240

1433F
14-3-3 protein eta

2

6

High-throughput

0.611

High

999797

DLG3
Disks large homolog 3

2

20

High-throughput

0.611

High

1015002

ARF5
ADP-ribosylation factor 5

2

2

High-throughput

0.611

High

1023455

ARVC
Splicing regulator ARVCF

2

5

High-throughput

0.611

High

1036090

CTNB1
Catenin beta-1

2

1

High-throughput

0.611

High

1042569

NMDE4
Glutamate receptor ionotropic, NMDA 2D

2

12

High-throughput

0.611

High

1189354

IQEC3
IQ motif and SEC7 domain-containing protein 3

2

3

High-throughput

0.611

High

1190104

DAB2P
Disabled homolog 2-interacting protein

2

9

High-throughput

0.611

High

1190858

SRBS2
Sorbin and SH3 domain-containing protein 2

2

20

High-throughput

0.611

High

1210253

CYFP2
Cytoplasmic FMR1-interacting protein 2

2

2

High-throughput

0.611

High

1222746

KCNA4
Potassium voltage-gated channel subfamily A member 4

2

2

High-throughput

0.611

High

1223956

SPTB2
Spectrin beta chain, non-erythrocytic 1

2

3

High-throughput

0.611

High

1224147

SRBS1
Sorbin and SH3 domain-containing protein 1

2

20

High-throughput

0.611

High

1224632

MK03
Mitogen-activated protein kinase 3

2

1

High-throughput

0.611

High

1229307

GIT1
ARF GTPase-activating protein GIT1

2

6

High-throughput

0.611

High

1229321

Q68FG2
Spectrin beta chain

2

3

High-throughput

0.611

High

1281874

LRRC7
Leucine-rich repeat-containing protein 7

2

1

High-throughput

0.611

High

1282919

LRC15
Leucine-rich repeat-containing protein 15

2

2

High-throughput

0.611

High

1282984

CNKR2
Connector enhancer of kinase suppressor of ras 2

2

12

High-throughput

0.611

High

1283245

AGRB3
Adhesion G protein-coupled receptor B3

2

1

High-throughput

0.611

High

1283515

DLG1
Disks large homolog 1

2

20

High-throughput

0.611

High

1298574

AGRB2
Adhesion G protein-coupled receptor B2

2

1

High-throughput

0.611

High

1317423

ABLM1
Actin-binding LIM protein 1

2

5

High-throughput

0.611

High

1341637

SH3K1
SH3 domain-containing kinase-binding protein 1

2

14

High-throughput

0.611

High

1353862

MPDZ
Multiple PDZ domain protein

2

20

High-throughput

0.611

High

1362349

DLG2
Disks large homolog 2

2

20

High-throughput

0.611

High

1363063

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

2

9

High-throughput

0.611

High

1423748

1433B
14-3-3 protein beta/alpha

2

6

High-throughput

0.611

High

1424056

MINK1
Misshapen-like kinase 1

2

6

High-throughput

0.611

High

1424057

KCJ10
ATP-sensitive inward rectifier potassium channel 10

2

3

High-throughput

0.611

High

1424063

E41L3
Band 4.1-like protein 3

2

4

High-throughput

0.611

High

1424066

E41L1
Band 4.1-like protein 1

2

3

High-throughput

0.611

High

1424067

SEPT5
Septin-5

2

4

High-throughput

0.611

High

1424069

HOME1
Homer protein homolog 1

2

4

High-throughput

0.611

High

60122

KALRN
Kalirin

3

6

High-throughput

0.599

High

67269

ITIH4
Inter alpha-trypsin inhibitor, heavy chain 4

2

0

High-throughput

0.585

High

147578

DPYL2
Dihydropyrimidinase-related protein 2

2

0

High-throughput

0.585

High

470784

NFL
Neurofilament light polypeptide

2

0

High-throughput

0.585

High

559583

GELS
Gelsolin

2

0

High-throughput

0.585

High

578759

GLNA
Glutamine synthetase

2

0

High-throughput

0.585

High

1223135

GDIB
Rab GDP dissociation inhibitor beta

2

0

High-throughput

0.585

High

1237820

FBX41
F-box only protein 41

2

0

High-throughput

0.585

High

1281937

DEND
Dendrin

2

0

High-throughput

0.585

High

1281947

AUXI
Auxilin

2

0

High-throughput

0.585

High

1283521

RHG32
Rho GTPase-activating protein 32

2

0

High-throughput

0.585

High

1424053

NBEA
Neurobeachin

2

0

High-throughput

0.585

High

1424062

ARC
Activity-regulated cytoskeleton-associated protein

2

0

High-throughput

0.585

High

1189606

Q3TTI9
Phosphodiesterase

2

1

High-throughput

0.584

High

1247195

NEB2
Neurabin-2

2

20

High-throughput

0.584

High

1423799

NRX1A
Neurexin-1

2

1

High-throughput

0.584

High

107111

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

2

3

High-throughput

0.558

High

704822

KIF5C
Kinesin heavy chain isoform 5C

2

2

High-throughput

0.558

High

757467

FAK1
Focal adhesion kinase 1

2

13

High-throughput

0.558

High

958848

ARF3
ADP-ribosylation factor 3

2

2

High-throughput

0.558

High

967127

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

2

6

High-throughput

0.558

High

990051

1433Z
14-3-3 protein zeta/delta

2

6

High-throughput

0.558

High

993986

PP2BA
Protein phosphatase 3 catalytic subunit alpha

2

6

High-throughput

0.558

High

1013701

TNIK
Traf2 and NCK-interacting protein kinase

2

6

High-throughput

0.558

High

1071144

TRIO
Triple functional domain protein

2

6

High-throughput

0.558

High

1190776

IQGA2
Ras GTPase-activating-like protein IQGAP2

2

9

High-throughput

0.558

High

1204112

IQEC2
IQ motif and SEC7 domain-containing protein 2

2

3

High-throughput

0.558

High

1243451

CSKI1
Caskin-1

2

1

High-throughput

0.558

High

1244508

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

2

9

High-throughput

0.558

High

1253345

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme UBE2O

2

1

High-throughput

0.558

High

1257343

SYNE1
Nesprin-1

2

4

High-throughput

0.558

High

1274215

CYFP1
Cytoplasmic FMR1-interacting protein 1

2

2

High-throughput

0.558

High

1281886

ERBIN
Erbin

2

1

High-throughput

0.558

High

1296913

BAIP2
BAR/IMD domain-containing adapter protein 2

2

2

High-throughput

0.558

High

1297996

SEP11
Septin-11

2

4

High-throughput

0.558

High

1341467

IQEC1
IQ motif and SEC7 domain-containing protein 1

2

3

High-throughput

0.558

High

1341701

WASF1
Actin-binding protein WASF1

2

1

High-throughput

0.558

High

1424055

LGI1
Leucine-rich glioma-inactivated protein 1

2

2

High-throughput

0.558

High

1424065

SEPT3
Neuronal-specific septin-3

2

4

High-throughput

0.558

High

1424068

GRIA3
Glutamate receptor 3

2

7

High-throughput

0.558

High

267278

CSKP
Peripheral plasma membrane protein CASK

1

20

High-throughput

0.536

High

312069

KCNJ1
ATP-sensitive inward rectifier potassium channel 1

1

3

High-throughput

0.536

High

548971

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

9

High-throughput

0.536

High

968204

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

5

High-throughput

0.536

High

1408733

HOME3
Homer protein homolog 3

1

5

High-throughput

0.536

High

1424058

DREB
Drebrin

1

2

High-throughput

0.536

High

86366

B9EKJ1
Spectrin alpha chain, non-erythrocytic 1

2

3

High-throughput

0.533

High

1081340

Q0VAV5
RAS protein activator like 2

2

9

High-throughput

0.533

High

1190803

Q3URF1
Synaptopodin

2

1

High-throughput

0.533

High

1424059

Q9QYK8
Inward rectifier potassium channel 3

2

3

High-throughput

0.533

High

1221915

CAPR1
Caprin-1

1

0

High-throughput

0.513

High

1222998

AP180
Clathrin coat assembly protein AP180

1

0

High-throughput

0.513

High

59756

SKT
Sickle tail protein

1

2

High-throughput

0.489

High

704839

KIF2A
Kinesin-like protein KIF2A

1

1

High-throughput

0.489

High

749857

KIF5A
Kinesin heavy chain isoform 5A

1

2

High-throughput

0.489

High

840634

PURA
Transcriptional activator protein Pur-alpha

1

1

High-throughput

0.489

High

1000349

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

1

High-throughput

0.489

High

1021948

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

2

High-throughput

0.489

High

1223088

FXR1
RNA-binding protein FXR1

1

4

High-throughput

0.489

High

1274329

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

High-throughput

0.489

High

1296950

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

10

High-throughput

0.489

High

1317345

LRRT1
Leucine-rich repeat transmembrane neuronal protein 1

1

3

High-throughput

0.489

High

1423734

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

2

High-throughput

0.489

High

663048

GRIA1
Glutamate receptor 1

1

7

High-throughput

0.479

High

1021648

RGS14
Regulator of G-protein signaling 14

1

3

High-throughput

0.479

High

1221834

SC6A4
Sodium-dependent serotonin transporter

1

3

High-throughput

0.479

High

1222688

CTNA2
Catenin alpha-2

1

0

High-throughput

0.458

High

73054

B1AWC9
Phosphodiesterase

1

1

High-throughput

0.445

High

777997

FMR1
Fragile X messenger ribonucleoprotein 1

1

4

High-throughput

0.445

High

1298241

SYNPO
Synaptopodin

1

1

High-throughput

0.445

High

97751

E9PXB7
E3 ubiquitin-protein ligase

1

2

High-throughput

0.437

High

1190907

CDKL5
Cyclin-dependent kinase-like 5

1

7

High-throughput

0.437

High

1230607

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

1

High-throughput

0.437

High

1296326

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

4

High-throughput

0.437

High

1297184

Q8BPK8
Fragile X messenger ribonucleoprotein 1

1

4

High-throughput

0.437

High

97699

E9PW37
RAS protein activator like 2

1

9

High-throughput

0.407

High

597665

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

3

High-throughput

0.407

High

909980

KCNJ4
Inward rectifier potassium channel 4

1

3

High-throughput

0.407

High

1298423

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

2

High-throughput

0.407

High

104773

F7BAB2
Transmembrane protein 132B

2

0

High-throughput

0.318

High

148360

DIAP1
Protein diaphanous homolog 1

2

0

High-throughput

0.318

High

704300

NCKP1
Nck-associated protein 1

2

0

High-throughput

0.318

High

810538

DYN1
Dynamin-1

2

0

High-throughput

0.318

High

866608

CAZA2
F-actin-capping protein subunit alpha-2

2

0

High-throughput

0.318

High

878607

CTRO
Citron Rho-interacting kinase

2

0

High-throughput

0.318

High

947838

RHG39
Rho GTPase-activating protein 39

2

0

High-throughput

0.318

High

957894

UBE2N
Ubiquitin-conjugating enzyme E2 N

2

0

High-throughput

0.318

High

981418

RAB1A
Ras-related protein Rab-1A

2

0

High-throughput

0.318

High

990955

KCAB1
Voltage-gated potassium channel subunit beta-1

2

0

High-throughput

0.318

High

1021400

MPRIP
Myosin phosphatase Rho-interacting protein

2

0

High-throughput

0.318

High

1229236

BEGIN
Brain-enriched guanylate kinase-associated protein

2

0

High-throughput

0.318

High

1282064

FBX2
F-box only protein 2

2

0

High-throughput

0.318

High

1297645

DZAN1
Double zinc ribbon and ankyrin repeat-containing protein 1

2

0

High-throughput

0.318

High

1424054

RPGF4
Rap guanine nucleotide exchange factor 4

2

0

High-throughput

0.318

High

1424060

DEST
Destrin

2

0

High-throughput

0.318

High

1424061

ADA22
Disintegrin and metalloproteinase domain-containing protein 22

2

0

High-throughput

0.318

High

313046

DCX
Neuronal migration protein doublecortin

1

0

High-throughput

0.279

Low

1233088

ABTB3
Ankyrin repeat- and BTB/POZ domain-containing protein 3

1

0

High-throughput

0.279

Low

1281915

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.279

Low

1424064

NCDN
Neurochondrin

1

0

High-throughput

0.279

Low

644436

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

0

High-throughput

0.249

Low

1282831

SPAT7
Spermatogenesis-associated protein 7 homolog

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025