HitPredict

Interactor 1: Q77NN8 (Q77NN8)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: ORF61

Interactor 2: Q77NN8 (Q77NN8)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: ORF61

Species: Human herpesvirus 3 strain Oka vaccine

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	20205919
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000209 - protein polyubiquitination GO:0006513 - protein monoubiquitination GO:0039648 - symbiont-mediated perturbation of host ubiquitin-like protein modification GO:0046872 - metal ion binding GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 467 Hh			1 467
+	Hs
		1345302 TOPRS_HUMAN (3-313): 1.74e-56: 204: 21.91		TOPRS_HUMAN (3-313): 1.74e-56: 204: 21.91
+	Mm
		1131451 ZNRF3_MOUSE (12-310): 1.48e-51: 189: 16.06		ZNRF3_MOUSE (12-310): 1.48e-51: 189: 16.06
+	Hs
		1345432 RAD18_HUMAN (19-312): 8.47e-54: 189: 14.38		RAD18_HUMAN (19-312): 8.47e-54: 189: 14.38
+	Hs
		1290116 CHFR_HUMAN (2-213): 1.6e-51: 186: 21.43		CHFR_HUMAN (2-213): 1.6e-51: 186: 21.43
+	Hs
		1356609 AMFR_HUMAN (1-305): 7.92e-43: 162: 14.24		AMFR_HUMAN (1-305): 7.92e-43: 162: 14.24
+	Hs
		1356983 ZNRF3_HUMAN (19-307): 3.88e-42: 162: 14.95		ZNRF3_HUMAN (19-307): 3.88e-42: 162: 14.95
+	Hs
		1148266 ZNRF3_HUMAN (19-307): 3.88e-42: 162: 14.95		RNF43_HUMAN (9-227): 4.62e-39: 152: 21.93
+	Hs
		1148095 RNF43_HUMAN (9-227): 4.62e-39: 152: 21.93		RNF43_HUMAN (9-227): 4.62e-39: 152: 21.93
+	Hs
		1240830 AMFR_HUMAN (1-305): 7.92e-43: 162: 14.24		RN149_HUMAN (5-84): 7.77e-22: 98.9: 23.17
+	Xl
		1117305 ZNRF3_XENLA (12-308): 1.8e-28: 120: 16.57		ZNRF3_XENLA (12-308): 1.8e-28: 120: 16.57
+	Hs
		1283411 RN166_HUMAN (2-205): 5.24e-30: 118: 16.98		RN166_HUMAN (2-205): 5.24e-30: 118: 16.98
+	Hs
		1255974 RN128_HUMAN (5-162): 1.12e-27: 116: 15.00		RN128_HUMAN (5-162): 1.12e-27: 116: 15.00
+	At
		1340218 ATL55_ARATH (3-174): 1.37e-28: 116: 20.22		ATL55_ARATH (3-174): 1.37e-28: 116: 20.22
+	Hs
		1240693 RN128_HUMAN (5-162): 1.12e-27: 116: 15.00		RN149_HUMAN (5-84): 7.77e-22: 98.9: 23.17
+	Hs
		1240704 RN133_HUMAN (4-126): 1.47e-25: 109: 18.46		RN149_HUMAN (5-84): 7.77e-22: 98.9: 23.17
+	Hs
		1304059 RING2_HUMAN (9-222): 7.95e-23: 100: 15.72		RING2_HUMAN (9-222): 7.95e-23: 100: 15.72
+	Mm
		1321732 RING2_MOUSE (9-222): 1.76e-22: 100: 15.72		RING2_MOUSE (9-222): 1.76e-22: 100: 15.72
+	Hs
		1240680 RN149_HUMAN (5-84): 7.77e-22: 98.9: 23.17		RN149_HUMAN (5-84): 7.77e-22: 98.9: 23.17