HitPredict

Interactor 1: SNP23 (O00161)
Synaptosomal-associated protein 23 (SNAP-23) (Vesicle-membrane fusion protein SNAP-23)
Gene: SNAP23

Interactor 2: STX11 (O75558)
Syntaxin-11
Gene: STX11

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	0.60	0.760

Property	Details
Experiments	25416956, 16189514, 25748427, 28514442, 33961781, 32296183, 10036234, 21900206, 25244094, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, validated two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0031201 - SNARE complex GO:0031629 - synaptic vesicle fusion to presynaptic active zone membrane and 1 others more... GO:0061025 - membrane fusion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Hs			1 287
+	Hs
		118010 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX1B_HUMAN (1-286): 1.32e-71: 223: 32.17
+	Hs
		118037 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX1A_HUMAN (1-286): 2.81e-70: 220: 28.67
+	Rn
		250768 SNP23_RAT (1-211): 6.18e-69: 211: 87.20		STX1B_RAT (1-286): 1.32e-71: 223: 32.17
+	Hs
		117977 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX2_HUMAN (1-286): 7.63e-68: 214: 31.82
+	Mm
		140165 SNP23_MOUSE (1-211): 2.55e-68: 209: 87.20		STX1A_MOUSE (1-286): 2.38e-71: 223: 28.67
+	Hs
		66335 A8K287_HUMAN (1-211): 1.06e-71: 218: 100.00		STX11_HUMAN (1-287): 1.26e-63: 203: 100.00
+	Hs
		118025 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX4_HUMAN (1-286): 1.54e-58: 190: 27.53
+	Dm
		1098103 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		STX1A_DROME (10-286): 7.18e-68: 214: 26.72
+	Hs
		118028 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX3_HUMAN (1-276): 4.38e-55: 181: 30.44
+	Rn
		250772 SNP23_RAT (1-211): 6.18e-69: 211: 87.20		STX4_RAT (1-286): 3.78e-55: 182: 26.48
+	Rn
		250771 SNP23_RAT (1-211): 6.18e-69: 211: 87.20		STX3_RAT (1-276): 7.66e-54: 178: 29.71
+	Mm
		140169 SNP23_MOUSE (1-211): 2.55e-68: 209: 87.20		STX3_MOUSE (1-276): 1.37e-53: 177: 29.71
+	At
		1351792 SNP33_ARATH (1-210): 2.42e-60: 192: 22.54		SY121_ARATH (17-278): 3.4e-54: 181: 18.59
+	Hs
		117929 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX7_HUMAN (56-275): 1e-44: 154: 15.25
+	Hs
		118048 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX12_HUMAN (47-283): 7.51e-44: 152: 19.09
+	Hs
		118053 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX19_HUMAN (1-278): 6.69e-42: 147: 35.92
+	At
		1114737 SNP33_ARATH (1-210): 2.42e-60: 192: 22.54		SY111_ARATH (1-278): 1.35e-47: 162: 17.25
+	Dm
		1098004 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		STX5_DROME (2-280): 2.25e-43: 155: 12.08
+	Dm
		1366722 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		Q9VR90_DROME (10-284): 1.8e-43: 153: 13.37
+	Dm
		1182812 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		STX4_DROME (28-279): 4.61e-43: 151: 17.86