Protein: TRIM9
E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING finger protein 91) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif-containing protein 9)

Gene: TRIM9
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q9C026

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005856 - cytoskeleton
GO:0008021 - synaptic vesicle
GO:0008270 - zinc ion binding
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1420548

FBW1A
F-box/WD repeat-containing protein 1A

12

16

Small-scale

0.982

High

1420546

FBW1B
F-box/WD repeat-containing protein 11

6

16

Small-scale

0.945

High

1420535

TRIM9
E3 ubiquitin-protein ligase TRIM9

4

19

Small-scale

0.874

High

877222

KC1D
Casein kinase I isoform delta

1

16

High-throughput

0.740

High

572194

TRI27
Zinc finger protein RFP

1

18

High-throughput

0.698

High

1165314

LONF1
LON peptidase N-terminal domain and RING finger protein 1

1

18

High-throughput

0.698

High

1278501

TRI46
Tripartite motif-containing protein 46

1

19

High-throughput

0.698

High

1350947

DTX3L
E3 ubiquitin-protein ligase DTX3L

1

4

High-throughput

0.698

High

1382337

RN166
E3 ubiquitin-protein ligase RNF166

1

20

High-throughput

0.698

High

1417949

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

18

High-throughput

0.698

High

1420179

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

19

High-throughput

0.698

High

1420552

ARI1
E3 ubiquitin-protein ligase ARIH1

1

16

High-throughput

0.691

High

1420544

EVL
Ena/VASP-like protein

3

10

High-throughput

0.675

High

845991

DCC
Netrin receptor DCC

2

17

Small-scale

0.675

High

423110

A4
Amyloid-beta precursor protein

1

13

High-throughput

0.665

High

1341232

IKBD
NF-kappa-B inhibitor delta

1

20

High-throughput

0.662

High

1399897

TSSK3
Testis-specific serine/threonine-protein kinase 3

1

6

High-throughput

0.662

High

1420540

EXOC1
Exocyst complex component 1

3

1

Small-scale

0.645

High

896632

VASP
Vasodilator-stimulated phosphoprotein

4

9

High-throughput

0.633

High

1292079

SPA24
Spermatogenesis-associated protein 24

2

1

High-throughput

0.628

High

954410

SNP25
Synaptosomal-associated protein 25

2

1

Small-scale

0.624

High

1420547

FBXW2
F-box/WD repeat-containing protein 2

1

20

High-throughput

0.618

High

170338

AURKA
Aurora kinase A

1

15

High-throughput

0.618

High

208732

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

9

Small-scale

0.618

High

626355

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

20

High-throughput

0.618

High

724422

COR1A
Coronin-1A

1

20

Small-scale

0.618

High

1163869

DUS6
Dual specificity protein phosphatase 6

1

8

Small-scale

0.618

High

1220778

RN123
E3 ubiquitin-protein ligase RNF123

1

18

High-throughput

0.618

High

1255428

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

1259481

TBA1A
Tubulin alpha-1A chain

1

20

High-throughput

0.618

High

1420543

TBK1
Serine/threonine-protein kinase TBK1

1

20

Small-scale

0.618

High

1420551

GRIP1
Glutamate receptor-interacting protein 1

1

20

Small-scale

0.618

High

1420553

MYO16
Unconventional myosin-XVI

1

20

Small-scale

0.618

High

1180491

C19L2
CWF19-like protein 2

3

7

High-throughput

0.616

High

1420542

SPG21
Maspardin

3

4

High-throughput

0.616

High

329103

KLHL2
Kelch-like protein 2

2

9

High-throughput

0.611

High

1326408

STX19
Syntaxin-19

3

7

High-throughput

0.609

High

337809

SGPL1
Sphingosine-1-phosphate lyase 1

2

6

High-throughput

0.574

High

1334454

RELL2
RELT-like protein 2

2

2

High-throughput

0.574

High

1381393

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

12

High-throughput

0.573

High

1228322

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

2

2

High-throughput

0.553

High

1295104

F90A1
Protein FAM90A1

2

6

High-throughput

0.553

High

1392895

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

7

High-throughput

0.553

High

1420538

F124B
Protein FAM124B

2

4

High-throughput

0.553

High

952466

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

20

Small-scale

0.553

High

1034333

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

16

High-throughput

0.553

High

572850

NCF1
Neutrophil cytosol factor 1

1

17

High-throughput

0.541

High

908781

MAT1
CDK-activating kinase assembly factor MAT1

1

8

High-throughput

0.541

High

1028381

MDM2
E3 ubiquitin-protein ligase Mdm2

1

7

High-throughput

0.541

High

1185945

PCGF3
Polycomb group RING finger protein 3

1

20

High-throughput

0.541

High

1389448

CHFR
E3 ubiquitin-protein ligase CHFR

1

20

High-throughput

0.541

High

570586

GFAP
Glial fibrillary acidic protein

1

20

High-throughput

0.536

High

727507

ZEP2
Transcription factor HIVEP2

1

20

High-throughput

0.536

High

1091036

BFSP1
Filensin

1

20

High-throughput

0.536

High

1112701

CUL1
Cullin-1

1

20

High-throughput

0.536

High

1112983

CUL2
Cullin-2

1

20

High-throughput

0.536

High

1230244

K1C40
Keratin, type I cytoskeletal 40

1

20

High-throughput

0.536

High

3431

A0A0S2Z507
Beta-transducin repeat containing isoform 3

1

15

High-throughput

0.528

High

85137

B7Z3H4
Beta-transducin repeat containing E3 ubiquitin protein ligase

1

16

High-throughput

0.528

High

1381119

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

15

High-throughput

0.523

High

1420550

AP3M1
AP-3 complex subunit mu-1

1

13

High-throughput

0.523

High

246129

KIF1B
Kinesin-like protein KIF1B

1

20

High-throughput

0.515

High

927532

ATX1
Ataxin-1

1

2

High-throughput

0.515

High

874000

NRIP1
Nuclear receptor-interacting protein 1

1

1

High-throughput

0.494

High

1420536

SEM4C
Semaphorin-4C

1

4

High-throughput

0.489

High

288509

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

20

High-throughput

0.481

High

1389795

DTBP1
Dysbindin

1

6

High-throughput

0.481

High

1420545

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

20

High-throughput

0.481

High

461903

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

537860

HSP7C
Heat shock cognate 71 kDa protein

1

16

High-throughput

0.479

High

552687

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

7

High-throughput

0.479

High

730869

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

790094

ZEB1
Zinc finger E-box-binding homeobox 1

1

20

Small-scale

0.479

High

935101

TERA
Transitional endoplasmic reticulum ATPase

1

11

Small-scale

0.479

High

953082

ACTB
Actin, cytoplasmic 1

1

20

High-throughput

0.479

High

971969

1433E
14-3-3 protein epsilon

1

4

High-throughput

0.479

High

977821

ACTA
Actin, aortic smooth muscle

1

20

Small-scale

0.479

High

995807

ACTC
Actin, alpha cardiac muscle 1

1

20

High-throughput

0.479

High

1085109

KIF1A
Kinesin-like protein KIF1A

1

20

Small-scale

0.479

High

1108120

SQSTM
Sequestosome-1

1

18

High-throughput

0.479

High

1114228

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1229070

RNF43
E3 ubiquitin-protein ligase RNF43

1

5

High-throughput

0.479

High

1310640

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

20

High-throughput

0.479

High

1420537

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1420539

RGS18
Regulator of G-protein signaling 18

1

3

High-throughput

0.479

High

1420549

ADIP
Afadin- and alpha-actinin-binding protein

1

3

High-throughput

0.479

High

1096214

TADBP
TAR DNA-binding protein 43

1

20

High-throughput

0.470

High

785426

RL4
Large ribosomal subunit protein uL4

1

6

High-throughput

0.457

High

1056953

FMR1
Fragile X messenger ribonucleoprotein 1

1

14

High-throughput

0.457

High

1085379

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

19

Small-scale

0.437

High

1203253

ODFP2
Outer dense fiber protein 2

1

20

High-throughput

0.437

High

1256582

CE128
Centrosomal protein of 128 kDa

1

20

High-throughput

0.437

High

1275319

PLPR4
Phospholipid phosphatase-related protein type 4

1

4

Small-scale

0.437

High

1289604

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.437

High

1414847

SCMC3
Mitochondrial adenyl nucleotide antiporter SLC25A23

1

20

Small-scale

0.437

High

1420541

CUED1
CUE domain-containing protein 1

1

1

High-throughput

0.437

High

1351586

MIPT3
TRAF3-interacting protein 1

1

8

High-throughput

0.417

High

94330

D6R9G5
Kelch like family member 2

1

12

High-throughput

0.407

High


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Last updated: 11Aug2025