Interactor 1: S4A8 (Q2Y0W8)
Electroneutral sodium bicarbonate exchanger 1 (Electroneutral Na(+)-driven Cl-HCO3 exchanger) (Solute carrier family 4 member 8) (k-NBC3)
Gene: SLC4A8
Interactor 2: S4A7 (Q9Y6M7)
Sodium bicarbonate cotransporter 3 (Electroneutral Na/HCO(3) cotransporter) (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7)
Gene: SLC4A7
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.73 | 1.00 | 0.855 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 33961781, unassigned3795 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Band_3_cyto~Band_3_cyto, Band_3_cyto~HCO3_cotransp, HCO3_cotransp~HCO3_cotransp |
| Common GO terms | GO:0005452 - solute:inorganic anion antiporter activity GO:0005886 - plasma membrane GO:0008510 - sodium:bicarbonate symporter activity GO:0015701 - bicarbonate transport GO:0016020 - membrane and 4 others more... |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
