Interactor 1: S4A8 (Q2Y0W8)
Electroneutral sodium bicarbonate exchanger 1 (Electroneutral Na(+)-driven Cl-HCO3 exchanger) (Solute carrier family 4 member 8) (k-NBC3)
Gene: SLC4A8

Interactor 2: S4A4 (Q9Y6R1)
Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1)
Gene: SLC4A4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments unassigned3795
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Band_3_cyto~Band_3_cyto, Band_3_cyto~HCO3_cotransp, HCO3_cotransp~HCO3_cotransp
Common GO terms GO:0005452 - solute:inorganic anion antiporter activity
GO:0005886 - plasma membrane
GO:0008510 - sodium:bicarbonate symporter activity
GO:0015701 - bicarbonate transport
GO:0016020 - membrane
and 6 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1093
Hs

1 1079
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025