HitPredict

Interactor 1: DMC1 (Q39009)
Meiotic recombination protein DMC1 homolog (AtDMC1)
Gene: DMC1

Interactor 2: BRC2A (Q7Y1C5)
Protein BREAST CANCER SUSCEPTIBILITY 2 homolog A (AtBRCA2A)
Gene: BRCA2A

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.826

Property	Details
Experiments	15014444, 16415210
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	BRCA2~Rad51
Common GO terms	GO:0003677 - DNA binding GO:0051321 - meiotic cell cycle
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 344 At			1 1151
+	At
		1020882 RAD51_ARATH (8-344): 3.46e-126: 367: 50.30		BRC2B_ARATH (1-1151): 0: 1975: 94.20
+	At
		1020883 RAD51_ARATH (8-344): 3.46e-126: 367: 50.30		BRC2A_ARATH (1-1151): 0: 1972: 100.00
+	At
		1182900 DMC1_ARATH (1-344): 4.32e-124: 361: 100.00		BRC2B_ARATH (1-1151): 0: 1975: 94.20
+	Cl
		1320615 RAD51_CANLF (12-344): 1.87e-129: 375: 51.20		Q8MKI9_CANLF (503-1058): 0: 728: 27.32
+	Hs
		904277 RAD51_HUMAN (12-344): 2.92e-130: 377: 51.50		BRCA2_HUMAN (503-1058): 0: 721: 27.81
+	Hs
		904286 DMC1_HUMAN (9-344): 8.2e-118: 345: 59.88		BRCA2_HUMAN (503-1058): 0: 721: 27.81
+	Mm
		1022059 RAD51_MOUSE (12-344): 2.48e-130: 377: 51.79		BRCA2_MOUSE (17-1058): 0: 672: 21.85
+	Hs
		219070 RA51C_HUMAN (28-342): 3.42e-84: 261: 27.79		BRCA2_HUMAN (503-1058): 0: 721: 27.81
+	Hs
		219938 XRCC3_HUMAN (32-340): 4.63e-73: 231: 23.60		BRCA2_HUMAN (503-1058): 0: 721: 27.81
+	Mm
		205479 RA51B_MOUSE (29-339): 1.44e-85: 263: 24.56		BRCA2_MOUSE (17-1058): 0: 672: 21.85