HitPredict

Interactor 1: MARK2 (Q7KZI7)
Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)
Gene: MARK2

Interactor 2: TPX2 (Q9ULW0)
Targeting protein for Xklp2 (Differentially expressed in cancerous and non-cancerous lung cells 2) (DIL-2) (Hepatocellular carcinoma-associated antigen 519) (Hepatocellular carcinoma-associated antigen 90) (Protein fls353) (Restricted expression proliferation-associated protein 100) (p100)
Gene: TPX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Aurora-A_bind~Pkinase
Common GO terms	GO:0005654 - nucleoplasm GO:0030295 - protein kinase activator activity GO:0032147 - activation of protein kinase activity
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 788 Hs			1 747
+	Hs
		647981 MARK3_HUMAN (3-788): 0: 656: 60.40		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Hs
		1349679 MARK1_HUMAN (3-788): 0: 644: 63.22		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00