HitPredict

Interactor 1: Q7KZS0 (Q7KZS0)
SUMO-conjugating enzyme UBC9 (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I)
Gene: UBE2I

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UBA~UQ_con, UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 184 Hs			1 624
+	Hs
		930438 UBC9_HUMAN (1-158): 1.17e-69: 210: 86.71		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		1183320 Q7KZS0_HUMAN (1-184): 1.19e-72: 218: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		930454 UBC9_HUMAN (1-158): 1.17e-69: 210: 86.71		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		829086 UBE2A_HUMAN (1-157): 1.19e-68: 207: 36.31		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Dm
		639410 UBCD1_DROME (4-157): 1.35e-73: 219: 33.12		Q9VWD9_DROME (26-617): 4.15e-130: 395: 44.35
+	Hs
		895774 UB2D3_HUMAN (4-157): 8.42e-73: 217: 31.82		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		895773 UB2D3_HUMAN (4-157): 8.42e-73: 217: 31.82		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		70479 UB2E3_HUMAN (3-156): 2.76e-67: 205: 31.17		B2RDW1_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Sc
		819482 UBC7_YEAST (1-137): 3.8e-26: 99.8: 37.84		DSK2_YEAST (32-239): 1.13e-31: 128: 31.19