HitPredict

Interactor 1: STING (Q3TBT3)
Stimulator of interferon genes protein (mSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (MMITA) (Transmembrane protein 173)
Gene: Sting1

Interactor 2: AMFR (Q9R049)
E3 ubiquitin-protein ligase AMFR (EC 2.3.2.36) (Autocrine motility factor receptor) (AMF receptor) (RING-type E3 ubiquitin transferase AMFR)
Gene: AMFR

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32554809, 37099423
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 378 Mm			1 643
+	Hs
		1292888 STING_HUMAN (1-377): 0: 563: 69.05		AMFR_HUMAN (1-643): 0: 618: 94.40
+	Mm
		1189113 STING_MOUSE (1-378): 0: 595: 100.00		SYVN1_MOUSE (51-629): 3.07e-86: 283: 17.55
+	Mm
		1188345 STING_MOUSE (1-378): 0: 595: 100.00		RN139_MOUSE (84-419): 1.77e-69: 240: 17.92
+	Mm
		1189020 STING_MOUSE (1-378): 0: 595: 100.00		MGRN1_MOUSE (303-619): 8.16e-56: 200: 18.55
+	Mm
		651519 STING_MOUSE (1-378): 0: 595: 100.00		CBL_MOUSE (293-619): 2.11e-38: 154: 17.33
+	Mm
		1188074 STING_MOUSE (1-378): 0: 595: 100.00		RN149_MOUSE (268-420): 5.68e-28: 118: 15.43
+	Mm
		1188430 STING_MOUSE (1-378): 0: 595: 100.00		RNF24_MOUSE (273-400): 1.87e-23: 98.7: 22.14
+	Hs
		1292895 STING_HUMAN (1-377): 0: 563: 69.05		RN115_HUMAN (316-400): 5.51e-24: 104: 28.09