Interactor 1: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS
Interactor 2: STING (Q86WV6)
Stimulator of interferon genes protein (hSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Transmembrane protein 173)
Gene: STING1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.756 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22908223, 22312431, 24622840, 19416887, 18724357, 20080758, 20019757, 18818105, 22844514, 22911572, 22000020, 23542348 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002218 - activation of innate immune response GO:0002230 - positive regulation of defense response to virus by host GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway GO:0005741 - mitochondrial outer membrane GO:0019901 - protein kinase binding and 10 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
