Protein: NTRK2
BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)

Gene: NTRK2
Organism: Homo sapiens
Interactions: 137
UniProt ID: Q16620

Gene Ontology (top 5):
GO:0001570 - vasculogenesis
GO:0001764 - neuron migration
GO:0002020 - protease binding
GO:0005524 - ATP binding
GO:0005769 - early endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

619066

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

4

20

Small-scale

0.891

High

660267

BDNF
Neurotrophic factor BDNF precursor form

3

9

Small-scale

0.858

High

363343

EGFR
Epidermal growth factor receptor

3

20

High-throughput

0.843

High

757424

NTF4
Neurotrophin-4

3

9

Small-scale

0.834

High

711360

SHC1
SHC-transforming protein 1

3

20

Small-scale

0.834

High

1159521

SHC3
SHC-transforming protein 3

3

20

Small-scale

0.829

High

611146

PTN1
Tyrosine-protein phosphatase non-receptor type 1

2

20

Small-scale

0.792

High

699770

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

20

Small-scale

0.757

High

1159497

NTRK2
BDNF/NT-3 growth factors receptor

2

18

Small-scale

0.753

High

440578

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.724

High

1145737

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

Small-scale

0.724

High

1156959

NTRK3
NT-3 growth factor receptor

1

18

High-throughput

0.715

High

1158337

CDC37
Hsp90 co-chaperone Cdc37

1

20

High-throughput

0.691

High

222094

NCK2
Cytoplasmic protein NCK2

1

20

Small-scale

0.680

High

634970

NTF3
Neurotrophin-3

1

9

Small-scale

0.647

High

410873

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.621

High

1159549

SH2B1
SH2B adapter protein 1

1

20

Small-scale

0.621

High

1159520

FRS2
Fibroblast growth factor receptor substrate 2

2

20

Small-scale

0.619

High

67675

RHG32
Rho GTPase-activating protein 32

1

20

High-throughput

0.618

High

136394

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.618

High

155115

SOCS2
Suppressor of cytokine signaling 2

1

20

Small-scale

0.618

High

159214

ABLM1
Actin-binding LIM protein 1

1

12

High-throughput

0.618

High

296510

STAM2
Signal transducing adapter molecule 2

1

20

High-throughput

0.618

High

338623

AGRL2
Adhesion G protein-coupled receptor L2

1

7

High-throughput

0.618

High

461531

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

468422

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

594013

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.618

High

692072

MARK3
MAP/microtubule affinity-regulating kinase 3

1

18

High-throughput

0.618

High

710268

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

835683

KPCI
Protein kinase C iota type

1

20

High-throughput

0.618

High

987670

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

1006074

DLG4
Disks large homolog 4

1

20

Small-scale

0.618

High

1040305

DYST
Dystonin

1

20

High-throughput

0.618

High

1047559

NOTC2
Neurogenic locus notch homolog protein 2

1

20

High-throughput

0.618

High

1053671

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

High-throughput

0.618

High

1060782

ACK1
Activated CDC42 kinase 1

1

20

Small-scale

0.618

High

1090134

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

20

High-throughput

0.618

High

1095537

LIPA1
Liprin-alpha-1

1

19

High-throughput

0.618

High

1102330

GRB10
Growth factor receptor-bound protein 10

1

20

Small-scale

0.618

High

1106477

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.618

High

1159507

SHC4
SHC-transforming protein 4

1

20

Small-scale

0.618

High

1159508

MPRIP
Myosin phosphatase Rho-interacting protein

1

20

High-throughput

0.618

High

1159510

LIPB1
Liprin-beta-1

1

20

High-throughput

0.618

High

1159515

MINK1
Misshapen-like kinase 1

1

20

High-throughput

0.618

High

1159522

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

20

High-throughput

0.618

High

1159526

ERBIN
Erbin

1

20

High-throughput

0.618

High

1159541

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

20

High-throughput

0.618

High

1159545

E41L5
Band 4.1-like protein 5

1

20

High-throughput

0.618

High

1159553

DP13A
DCC-interacting protein 13-alpha

1

16

High-throughput

0.618

High

1159554

KDIS
Kinase D-interacting substrate of 220 kDa

1

20

High-throughput

0.618

High

1159556

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

20

High-throughput

0.618

High

1159529

SORT
Sortilin

1

7

Small-scale

0.589

High

1107763

SQSTM
Sequestosome-1

2

12

Small-scale

0.584

High

828216

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

15

Small-scale

0.578

High

1159504

PHLB3
Pleckstrin homology-like domain family B member 3

1

17

High-throughput

0.553

High

1159537

TARA
TRIO and F-actin-binding protein

1

20

High-throughput

0.553

High

1159557

ANR26
Ankyrin repeat domain-containing protein 26

1

18

High-throughput

0.553

High

1159532

NFIP1
NEDD4 family-interacting protein 1

1

2

Small-scale

0.552

High

1083240

AP1B1
AP-1 complex subunit beta-1

1

15

High-throughput

0.541

High

1159528

SCN2A
Sodium channel protein type 2 subunit alpha

1

9

High-throughput

0.536

High

1159544

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

1

0

High-throughput

0.518

High

1106554

SMAD4
Mothers against decapentaplegic homolog 4

1

4

High-throughput

0.506

High

475972

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

8

High-throughput

0.500

High

124785

AIP
AH receptor-interacting protein

1

18

High-throughput

0.479

High

167607

GIPC1
PDZ domain-containing protein GIPC1

1

4

Small-scale

0.479

High

169569

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

20

High-throughput

0.479

High

174246

ARHGA
Rho guanine nucleotide exchange factor 10

1

20

High-throughput

0.479

High

241813

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

269771

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

20

High-throughput

0.479

High

333025

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

20

High-throughput

0.479

High

336108

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

20

High-throughput

0.479

High

338481

SC24B
Protein transport protein Sec24B

1

20

High-throughput

0.479

High

404089

GCR
Glucocorticoid receptor

1

8

Small-scale

0.479

High

466579

TNR16
Tumor necrosis factor receptor superfamily member 16

1

14

Small-scale

0.479

High

627339

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

15

High-throughput

0.479

High

642898

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

6

Small-scale

0.479

High

791422

SYUA
Alpha-synuclein

1

3

Small-scale

0.479

High

839158

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

1

20

High-throughput

0.479

High

898083

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

20

High-throughput

0.479

High

983496

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

12

High-throughput

0.479

High

1036985

DSC2
Desmocollin-2

1

20

High-throughput

0.479

High

1037718

PAX5
Paired box protein Pax-5

1

1

Small-scale

0.479

High

1051667

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

5

Small-scale

0.479

High

1124821

FLOT2
Flotillin-2

1

16

High-throughput

0.479

High

1146304

L2GL1
Lethal(2) giant larvae protein homolog 1

1

7

High-throughput

0.479

High

1148978

SC23B
Protein transport protein Sec23B

1

20

High-throughput

0.479

High

1159498

OCLN
Occludin

1

6

High-throughput

0.479

High

1159499

GRDN
Girdin

1

20

High-throughput

0.479

High

1159500

PLCH1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

1

20

High-throughput

0.479

High

1159501

DCAF6
DDB1- and CUL4-associated factor 6

1

16

High-throughput

0.479

High

1159502

F1711
Protein FAM171A1

1

20

High-throughput

0.479

High

1159503

STEA3
Metalloreductase STEAP3

1

4

High-throughput

0.479

High

1159509

GRIN3
G protein-regulated inducer of neurite outgrowth 3

1

17

High-throughput

0.479

High

1159511

LSR
Lipolysis-stimulated lipoprotein receptor

1

8

High-throughput

0.479

High

1159512

DZIP1
Cilium assembly protein DZIP1

1

20

High-throughput

0.479

High

1159514

CBARP
Voltage-dependent calcium channel beta subunit-associated regulatory protein

1

2

High-throughput

0.479

High

1159516

CNNM3
Metal transporter CNNM3

1

4

High-throughput

0.479

High

1159517

VANG1
Vang-like protein 1

1

14

High-throughput

0.479

High

1159518

DLG5
Disks large homolog 5

1

20

High-throughput

0.479

High

1159519

PARD3
Partitioning defective 3 homolog

1

20

High-throughput

0.479

High

1159523

US6NL
USP6 N-terminal-like protein

1

20

High-throughput

0.479

High

1159527

RANB9
Ran-binding protein 9

1

10

Small-scale

0.479

High

1159530

CDCA3
Cell division cycle-associated protein 3

1

14

High-throughput

0.479

High

1159531

PKP2
Plakophilin-2

1

20

High-throughput

0.479

High

1159533

RFIP5
Rab11 family-interacting protein 5

1

16

High-throughput

0.479

High

1159534

SPY4
Protein sprouty homolog 4

1

7

High-throughput

0.479

High

1159535

ZDHC5
Palmitoyltransferase ZDHHC5

1

10

High-throughput

0.479

High

1159536

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

1159538

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

12

High-throughput

0.479

High

1159540

CENPH
Centromere protein H

1

2

High-throughput

0.479

High

1159543

PPIP2
Proline-serine-threonine phosphatase-interacting protein 2

1

20

High-throughput

0.479

High

1159546

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

20

High-throughput

0.479

High

1159547

JPH1
Junctophilin-1

1

10

High-throughput

0.479

High

1159548

WDR6
tRNA

1

20

High-throughput

0.479

High

1159551

S53A1
Solute carrier family 53 member 1

1

4

High-throughput

0.479

High

1159552

TRM7
tRNA

1

7

High-throughput

0.479

High

1159555

MYO6
Unconventional myosin-VI

1

12

High-throughput

0.479

High

1159558

NISCH
Nischarin

1

20

High-throughput

0.479

High

1159559

DTNA
Dystrobrevin alpha

1

12

High-throughput

0.479

High

1159560

TRAF6
TNF receptor-associated factor 6

1

13

Small-scale

0.479

High

1159562

S4A7
Sodium bicarbonate cotransporter 3

1

13

High-throughput

0.479

High

1063048

S20A2
Sodium-dependent phosphate transporter 2

1

0

High-throughput

0.458

High

255045

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

7

High-throughput

0.445

High

1119149

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

9

High-throughput

0.445

High

1159524

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

20

High-throughput

0.445

High

1159525

VPS35
Vacuolar protein sorting-associated protein 35

1

2

Small-scale

0.445

High

71328

F1712
Protein FAM171A2

1

20

High-throughput

0.437

High

1150908

TRIPB
Thyroid receptor-interacting protein 11

1

20

High-throughput

0.437

High

1159505

F171B
Protein FAM171B

1

20

High-throughput

0.437

High

1159506

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

9

High-throughput

0.437

High

1159513

M21D2
Nucleotidyltransferase MB21D2

1

8

High-throughput

0.437

High

1159539

GCP60
Golgi resident protein GCP60

1

16

High-throughput

0.437

High

1159542

GORS2
Golgi reassembly-stacking protein 2

1

15

High-throughput

0.437

High

1159550

F135A
Protein FAM135A

1

5

High-throughput

0.437

High

1159561

UBIA1
UbiA prenyltransferase domain-containing protein 1

1

1

High-throughput

0.437

High

976094

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025