HitPredict

Interactor 1: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 540 Hs			1 618
+	Hs
		545467 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		892454 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		894165 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		1070272 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		951111 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Mm
		925811 MAVS_MOUSE (1-538): 5.1e-46: 170: 47.68		RAC1_MOUSE (3-181): 3.15e-74: 237: 26.43
+	Hs
		297812 K0754_HUMAN (43-539): 5.17e-38: 151: 11.24		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		297819 K0754_HUMAN (43-539): 5.17e-38: 151: 11.24		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		297829 K0754_HUMAN (43-539): 5.17e-38: 151: 11.24		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		297827 K0754_HUMAN (43-539): 5.17e-38: 151: 11.24		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		1190085 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		RAB1B_HUMAN (416-578): 8.51e-39: 143: 19.05
+	Hs
		297823 K0754_HUMAN (43-539): 5.17e-38: 151: 11.24		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		914172 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		900632 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		120511 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		297822 K0754_HUMAN (43-539): 5.17e-38: 151: 11.24		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		297820 K0754_HUMAN (43-539): 5.17e-38: 151: 11.24		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		297841 K0754_HUMAN (43-539): 5.17e-38: 151: 11.24		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		297809 K0754_HUMAN (43-539): 5.17e-38: 151: 11.24		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120250 K0754_HUMAN (43-539): 5.17e-38: 151: 11.24		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89