HitPredict

Interactor 1: LRP10 (Q7Z4F1)
Low-density lipoprotein receptor-related protein 10 (LRP-10)
Gene: LRP10

Interactor 2: GGA1 (Q9UJY5)
ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1)
Gene: GGA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 713 Hs			1 639
+	Hs
		1190291 LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00		GGA3_HUMAN (6-639): 3.76e-158: 473: 48.47
+	Hs
		1190296 LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00		GGA2_HUMAN (3-637): 9.87e-155: 461: 46.78
+	Hs
		253923 LRP3_HUMAN (1-693): 5.95e-107: 344: 36.03		GGA1_HUMAN (1-639): 0: 562: 100.00
+	Hs
		253922 LRP3_HUMAN (1-693): 5.95e-107: 344: 36.03		GGA2_HUMAN (3-637): 9.87e-155: 461: 46.78
+	Hs
		1269037 SORL_HUMAN (305-535): 1.96e-22: 105: 14.48		GGA1_HUMAN (1-639): 0: 562: 100.00
+	Hs
		1048460 LRP8_HUMAN (89-230): 6.24e-11: 68: 19.46		GGA1_HUMAN (1-639): 0: 562: 100.00
+	Hs
		1269036 SORL_HUMAN (305-535): 1.96e-22: 105: 14.48		GGA2_HUMAN (3-637): 9.87e-155: 461: 46.78
+	Mm
		291365 SORL_MOUSE (306-535): 5.56e-22: 104: 14.53		GGA2_MOUSE (10-631): 1.5e-151: 452: 44.70