Interactor 1: ACY2 (P45381)
Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2)
Gene: ASPA

Interactor 2: ACY3 (Q96HD9)
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) (EC 3.5.1.114) (Acylase III) (Aminoacylase-3) (ACY-3) (Aspartoacylase-2) (Hepatitis C virus core-binding protein 1) (HCBP1) (HCV core-binding protein 1)
Gene: ACY3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.917

The method score is based on:

Property Details
Experiments 25416956, 25910212, 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, split luciferase complementation, two hybrid bait and prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AstE_AspA~AstE_AspA
Common GO terms GO:0005829 - cytosol
GO:0016788 - hydrolase activity, acting on ester bonds
GO:0046872 - metal ion binding
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 313
Hs

1 319
+ Hs
+ Rn
+ Hs
+ Mm

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Last updated: 15 Jul 2024