HitPredict

Interactor 1: ARHG8 (Q7Z628)
Neuroepithelial cell-transforming gene 1 protein (Proto-oncogene p65 Net1) (Rho guanine nucleotide exchange factor 8)
Gene: NET1

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34315543
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PX, PH~RA
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 596 Hs			1 541
+	Hs
		1136429 ARHG8_HUMAN (1-596): 6.4e-144: 431: 100.00		MAGI3_HUMAN (19-429): 6.34e-14: 77.3: 15.39
+	Hs
		1191351 ARHG8_HUMAN (1-596): 6.4e-144: 431: 100.00		MAGI1_HUMAN (2-334): 3.18e-13: 74.9: 17.51
+	Mm
		1164175 ARHG8_MOUSE (1-596): 6.46e-143: 428: 86.91		MAGI1_MOUSE (3-334): 2.71e-13: 74.9: 17.00
+	Hs
		1333801 ECT2_HUMAN (71-596): 8.41e-88: 293: 17.50		NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43
+	Hs
		1301988 ECT2_HUMAN (71-596): 8.41e-88: 293: 17.50		NEB2_HUMAN (40-314): 3.95e-34: 139: 17.98
+	Mm
		1115909 SPT13_MOUSE (14-567): 1.19e-99: 318: 18.39		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Hs
		548744 VAV_HUMAN (68-595): 1.74e-81: 275: 13.97		NEB2_HUMAN (40-314): 3.95e-34: 139: 17.98
+	Hs
		1287792 Q96D37_HUMAN (68-595): 1.02e-81: 274: 13.97		NEB2_HUMAN (40-314): 3.95e-34: 139: 17.98
+	Hs
		548755 VAV_HUMAN (68-595): 1.74e-81: 275: 13.97		LIN7C_HUMAN (35-136): 1.5e-27: 111: 34.95
+	Hs
		1288532 ARHGQ_HUMAN (24-496): 8.06e-81: 273: 18.33		LIN7B_HUMAN (34-136): 8.8e-28: 112: 34.62
+	Hs
		1288534 ARHGQ_HUMAN (24-496): 8.06e-81: 273: 18.33		LIN7C_HUMAN (35-136): 1.5e-27: 111: 34.95
+	Hs
		1075407 ITSN1_HUMAN (14-578): 4.13e-80: 277: 19.03		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		1078902 ITSN1_HUMAN (14-578): 4.13e-80: 277: 19.03		SHAN3_HUMAN (44-148): 1.57e-21: 101: 37.14
+	Mm
		57860 KALRN_MOUSE (147-567): 2.72e-58: 214: 16.90		Q7TN74_MOUSE (40-375): 2.98e-41: 161: 14.43
+	Mm
		1116034 NGEF_MOUSE (4-591): 3.25e-79: 266: 16.22		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Hs
		962568 ECT2L_HUMAN (116-500): 4.17e-63: 225: 20.44		NEB2_HUMAN (40-314): 3.95e-34: 139: 17.98
+	Hs
		990936 ECT2_HUMAN (71-596): 8.41e-88: 293: 17.50		ZO1_HUMAN (4-254): 7.48e-12: 70.3: 13.97
+	Hs
		1138663 ARHGG_HUMAN (121-496): 6.34e-74: 252: 19.80		LIN7C_HUMAN (35-136): 1.5e-27: 111: 34.95
+	Hs
		299264 FARP2_HUMAN (8-593): 4.7e-78: 269: 17.97		NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70
+	Mm
		57847 KALRN_MOUSE (147-567): 2.72e-58: 214: 16.90		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19