HitPredict

Interactor 1: YAP1 (Q45VV3)
Transcriptional coactivator yorkie (Protein yorkie) (Transcriptional coactivator YAP1 homolog)
Gene: yki

Interactor 2: CPSF6 (Q9VSH4)
Cleavage and polyadenylation specificity factor subunit 6
Gene: CPSF6

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24114784
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 395 Dm			1 652
+	Dm
		674020 YAP1_DROME (1-395): 3.19e-92: 284: 100.00		BRM_DROME (275-642): 1.44e-45: 176: 14.62
+	Hs
		1160290 WWP1_HUMAN (19-390): 6.43e-78: 260: 17.80		CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89
+	Hs
		1329105 WWP1_HUMAN (19-390): 6.43e-78: 260: 17.80		CPSF7_HUMAN (5-560): 4.3e-33: 134: 29.89
+	Hs
		1413308 WWP1_HUMAN (19-390): 6.43e-78: 260: 17.80		DIDO1_HUMAN (145-650): 1.49e-27: 121: 16.67
+	Hs
		1160306 SMUF1_HUMAN (52-380): 1.3e-70: 237: 20.16		CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89
+	Hs
		861931 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		SMCA2_HUMAN (104-630): 5.01e-43: 169: 15.30
+	Hs
		861932 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		SMCA4_HUMAN (149-630): 1.5e-42: 167: 14.77
+	Hs
		903257 SMUF2_HUMAN (71-347): 6.31e-48: 175: 17.42		SMCA2_HUMAN (104-630): 5.01e-43: 169: 15.30
+	Hs
		550167 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15
+	Hs
		862453 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		PABP3_HUMAN (79-364): 1.48e-36: 147: 12.59
+	Hs
		862180 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89
+	Hs
		862298 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		CPSF7_HUMAN (5-560): 4.3e-33: 134: 29.89
+	Hs
		862416 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		DIDO1_HUMAN (145-650): 1.49e-27: 121: 16.67
+	Hs
		1102117 WWOX_HUMAN (237-353): 9.96e-32: 126: 33.33		PABP4_HUMAN (79-363): 1.21e-44: 171: 11.79
+	Hs
		903500 WWOX_HUMAN (237-353): 9.96e-32: 126: 33.33		SMCA4_HUMAN (149-630): 1.5e-42: 167: 14.77
+	Hs
		550499 WWOX_HUMAN (237-353): 9.96e-32: 126: 33.33		PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15
+	Hs
		1160325 WWOX_HUMAN (237-353): 9.96e-32: 126: 33.33		CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89
+	Hs
		1206146 SAV1_HUMAN (24-366): 2.56e-38: 143: 17.48		TGO1_HUMAN (215-442): 4.5e-09: 61.9: 26.34
+	Hs
		925762 WWOX_HUMAN (237-353): 9.96e-32: 126: 33.33		SC24C_HUMAN (276-474): 3.53e-10: 65.5: 17.89
+	Hs
		1206164 WWOX_HUMAN (237-353): 9.96e-32: 126: 33.33		TGO1_HUMAN (215-442): 4.5e-09: 61.9: 26.34