HitPredict

Interactor 1: Q804D1 (Q804D1)
E3 SUMO-protein ligase CBX4 (Polycomb 2)
Gene: cbx4

Interactor 2: PHC2 (Q8QHL5)
Polyhomeotic-like protein 2
Gene: PHC2

Species: Danio rerio

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	21195142
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0035102 - PRC1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 477 Dr			1 827
+	Hs
		123280 CBX4_HUMAN (1-475): 9.88e-100: 312: 40.57		PHC2_HUMAN (1-827): 4.53e-54: 203: 38.86
+	Hs
		123234 CBX4_HUMAN (1-475): 9.88e-100: 312: 40.57		PHC1_HUMAN (8-827): 4.13e-45: 177: 23.37
+	Hs
		123303 CBX4_HUMAN (1-475): 9.88e-100: 312: 40.57		SCMH1_HUMAN (375-826): 2.51e-37: 151: 17.66
+	Hs
		123346 CBX4_HUMAN (1-475): 9.88e-100: 312: 40.57		SCML2_HUMAN (384-826): 1.53e-27: 121: 15.85
+	Hs
		1059170 CBX2_HUMAN (2-473): 1.2e-66: 225: 20.45		PHC2_HUMAN (1-827): 4.53e-54: 203: 38.86
+	Hs
		1220894 CBX8_HUMAN (1-394): 2.94e-59: 201: 19.37		PHC2_HUMAN (1-827): 4.53e-54: 203: 38.86
+	Hs
		943062 CBX2_HUMAN (2-473): 1.2e-66: 225: 20.45		PHC1_HUMAN (8-827): 4.13e-45: 177: 23.37
+	Mm
		675498 CBX2_MOUSE (2-473): 1.52e-68: 229: 20.08		PHC1_MOUSE (8-827): 3.51e-42: 168: 23.67
+	Hs
		316088 CBX6_HUMAN (1-393): 2.92e-55: 191: 19.80		PHC2_HUMAN (1-827): 4.53e-54: 203: 38.86
+	Hs
		943094 CBX8_HUMAN (1-394): 2.94e-59: 201: 19.37		PHC1_HUMAN (8-827): 4.13e-45: 177: 23.37
+	Hs
		1059182 CBX2_HUMAN (2-473): 1.2e-66: 225: 20.45		SCMH1_HUMAN (375-826): 2.51e-37: 151: 17.66
+	Hs
		123290 CBX4_HUMAN (1-475): 9.88e-100: 312: 40.57		PHC3_HUMAN (62-757): 4.46e-09: 62.2: 10.13
+	Hs
		316005 CBX6_HUMAN (1-393): 2.92e-55: 191: 19.80		PHC1_HUMAN (8-827): 4.13e-45: 177: 23.37
+	Hs
		1292155 CBX8_HUMAN (1-394): 2.94e-59: 201: 19.37		SCMH1_HUMAN (375-826): 2.51e-37: 151: 17.66
+	Hs
		1059204 CBX2_HUMAN (2-473): 1.2e-66: 225: 20.45		SCML2_HUMAN (384-826): 1.53e-27: 121: 15.85
+	Hs
		1335794 CBX8_HUMAN (1-394): 2.94e-59: 201: 19.37		SCML2_HUMAN (384-826): 1.53e-27: 121: 15.85
+	Hs
		1059207 CBX2_HUMAN (2-473): 1.2e-66: 225: 20.45		LMBL1_HUMAN (556-788): 1.25e-16: 86.8: 12.40
+	Mm
		675500 CBX2_MOUSE (2-473): 1.52e-68: 229: 20.08		PHC3_MOUSE (65-756): 5.86e-09: 61.8: 8.50
+	Hs
		1059177 CBX2_HUMAN (2-473): 1.2e-66: 225: 20.45		PHC3_HUMAN (62-757): 4.46e-09: 62.2: 10.13
+	Hs
		1242737 CBX8_HUMAN (1-394): 2.94e-59: 201: 19.37		PHC3_HUMAN (62-757): 4.46e-09: 62.2: 10.13