HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: RBP56 (Q92804)
TATA-binding protein-associated factor 2N (68 kDa TATA-binding protein-associated factor) (TAF(II)68) (TAFII68) (RNA-binding protein 56)
Gene: TAF15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	29845934, 29884807
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008380 - RNA splicing
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 592
+	Hs
		1033005 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		EWS_HUMAN (4-383): 3.75e-35: 142: 32.96
+	Hs
		775130 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		FUS_HUMAN (8-381): 2.74e-32: 132: 39.28
+	Hs
		225298 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		HTSF1_HUMAN (113-325): 5.61e-31: 130: 18.06
+	Hs
		1121788 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		EIF3A_HUMAN (314-591): 5.43e-22: 103: 18.21
+	Hs
		1102042 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		RBP56_HUMAN (1-394): 5.2e-37: 147: 100.00
+	Hs
		431095 LA_HUMAN (24-365): 5.99e-44: 163: 18.83		EWS_HUMAN (4-383): 3.75e-35: 142: 32.96
+	Hs
		550392 PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29		RBP56_HUMAN (1-394): 5.2e-37: 147: 100.00
+	Hs
		775060 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		FUS_HUMAN (8-381): 2.74e-32: 132: 39.28
+	Hs
		550147 PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29		FUS_HUMAN (8-381): 2.74e-32: 132: 39.28
+	Hs
		431126 LA_HUMAN (24-365): 5.99e-44: 163: 18.83		EIF3A_HUMAN (314-591): 5.43e-22: 103: 18.21
+	Hs
		1418651 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		RBMX2_HUMAN (227-440): 6.27e-28: 116: 19.36
+	Hs
		1451044 RBM28_HUMAN (40-343): 2.16e-23: 106: 13.84		RBMX2_HUMAN (227-440): 6.27e-28: 116: 19.36
+	Hs
		1245683 LARP1_HUMAN (29-114): 6.38e-13: 73.8: 40.23		RBP56_HUMAN (1-394): 5.2e-37: 147: 100.00
+	Hs
		1152570 ELAV1_HUMAN (92-211): 7.75e-13: 71.9: 22.50		RBP56_HUMAN (1-394): 5.2e-37: 147: 100.00
+	Hs
		1032992 ELAV1_HUMAN (92-211): 7.75e-13: 71.9: 22.50		EWS_HUMAN (4-383): 3.75e-35: 142: 32.96
+	Hs
		775157 LARP1_HUMAN (29-114): 6.38e-13: 73.8: 40.23		FUS_HUMAN (8-381): 2.74e-32: 132: 39.28
+	Hs
		775112 ELAV1_HUMAN (92-211): 7.75e-13: 71.9: 22.50		FUS_HUMAN (8-381): 2.74e-32: 132: 39.28