HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: RBM8A (Q9Y5S9)
RNA-binding protein 8A (Binder of OVCA1-1) (BOV-1) (RNA-binding motif protein 8A) (RNA-binding protein Y14) (Ribonucleoprotein RBM8A)
Gene: RBM8A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0008380 - RNA splicing
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 174
+	Hs
		1148502 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		SF3B4_HUMAN (67-155): 1.37e-25: 102: 26.97
+	Hs
		1194132 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		PAP1L_HUMAN (64-158): 6.73e-25: 101: 24.21
+	Hs
		1101980 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		PABP4_HUMAN (64-158): 7.08e-24: 99.1: 23.16
+	Hs
		550310 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		PABP1_HUMAN (64-158): 7.04e-24: 99.1: 23.16
+	Hs
		1194374 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		PABP3_HUMAN (64-158): 1.32e-21: 92.6: 23.16
+	Hs
		1126931 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		RBM39_HUMAN (26-172): 2.37e-18: 83: 14.97
+	Hs
		1102145 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		RBM8A_HUMAN (1-169): 5.35e-42: 140: 100.00
+	At
		306156 LRP6B_ARATH (2-265): 6.45e-54: 194: 21.20		PABP2_ARATH (57-162): 1.88e-23: 98: 19.81
+	At
		306158 LRP6B_ARATH (2-265): 6.45e-54: 194: 21.20		PABP8_ARATH (69-158): 4.22e-22: 94.1: 22.22
+	At
		842070 LRP6C_ARATH (12-249): 1.54e-49: 179: 23.14		PABP2_ARATH (57-162): 1.88e-23: 98: 19.81
+	Hs
		1197178 PABP3_HUMAN (1-333): 2.14e-42: 163: 10.11		PAP1L_HUMAN (64-158): 6.73e-25: 101: 24.21
+	Hs
		1102095 PABP3_HUMAN (1-333): 2.14e-42: 163: 10.11		PABP4_HUMAN (64-158): 7.08e-24: 99.1: 23.16
+	Hs
		431115 LA_HUMAN (24-365): 5.99e-44: 163: 18.83		PABP4_HUMAN (64-158): 7.08e-24: 99.1: 23.16
+	Hs
		550464 PABP3_HUMAN (1-333): 2.14e-42: 163: 10.11		PABP1_HUMAN (64-158): 7.04e-24: 99.1: 23.16
+	Hs
		550262 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		PABP1_HUMAN (64-158): 7.04e-24: 99.1: 23.16
+	Hs
		431128 LA_HUMAN (24-365): 5.99e-44: 163: 18.83		RBM39_HUMAN (26-172): 2.37e-18: 83: 14.97
+	Hs
		506129 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		PAB4L_HUMAN (73-151): 8.03e-19: 83.8: 26.58
+	Hs
		1101955 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		RBM39_HUMAN (26-172): 2.37e-18: 83: 14.97
+	Hs
		431278 LA_HUMAN (24-365): 5.99e-44: 163: 18.83		PPIE_HUMAN (74-160): 1.76e-17: 79.4: 31.03