Interactor 1: ACSF3 (Q4G176)
Malonate--CoA ligase ACSF3, mitochondrial (EC 6.2.1.76) (Acyl-CoA synthetase family member 3)
Gene: ACSF3

Interactor 2: ACSM5 (Q6NUN0)
Acyl-coenzyme A synthetase ACSM5, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 5)
Gene: ACSM5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AMP-binding~AMP-binding, AMP-binding~AMP-binding_C, AMP-binding_C~AMP-binding_C
Common GO terms GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006633 - fatty acid biosynthetic process
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 576
Hs

1 579
+ Hs
+ Mm
+ Sc
+ Cj
+ Mm
+ Hs
+ Ec
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025